Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DCHS2 (dachsous cadherin-related 2)

Identity

Alias_namesCDH27
PCDH23
cadherin-like 27
dachsous 2 (Drosophila)
Alias_symbol (synonym)CDHJ
FLJ20047
PCDHJ
CDHR7
Other alias
HGNC (Hugo) DCHS2
LocusID (NCBI) 54798
Atlas_Id 56683
Location 4q31.3  [Link to chromosome band 4q31]
Location_base_pair Starts at 154234375 and ends at 154491725 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DCHS2 (4q31.3) / FGG (4q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  DCHS2/FGG (4q31)

External links

Nomenclature
HGNC (Hugo)DCHS2   23111
Cards
Entrez_Gene (NCBI)DCHS2  54798  dachsous cadherin-related 2
AliasesCDH27; CDHJ; CDHR7; PCDH23; 
PCDHJ
GeneCards (Weizmann)DCHS2
Ensembl hg19 (Hinxton)ENSG00000197410 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197410 [Gene_View]  ENSG00000197410 [Sequence]  chr4:154234375-154491725 [Contig_View]  DCHS2 [Vega]
ICGC DataPortalENSG00000197410
TCGA cBioPortalDCHS2
AceView (NCBI)DCHS2
Genatlas (Paris)DCHS2
WikiGenes54798
SOURCE (Princeton)DCHS2
Genetics Home Reference (NIH)DCHS2
Genomic and cartography
GoldenPath hg38 (UCSC)DCHS2  -     chr4:154234375-154491725 -  4q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCHS2  -     4q31.3   [Description]    (hg19-Feb_2009)
GoldenPathDCHS2 - 4q31.3 [CytoView hg19]  DCHS2 - 4q31.3 [CytoView hg38]
ImmunoBaseENSG00000197410
Mapping of homologs : NCBIDCHS2 [Mapview hg19]  DCHS2 [Mapview hg38]
OMIM612486   
Gene and transcription
Genbank (Entrez)AF169691 AK000054 AK095103 AK127704 AK225200
RefSeq transcript (Entrez)NM_001142552 NM_001142553 NM_001358235 NM_017639 NM_199348
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCHS2
Cluster EST : UnigeneHs.655664 [ NCBI ]
CGAP (NCI)Hs.655664
Alternative Splicing GalleryENSG00000197410
Gene ExpressionDCHS2 [ NCBI-GEO ]   DCHS2 [ EBI - ARRAY_EXPRESS ]   DCHS2 [ SEEK ]   DCHS2 [ MEM ]
Gene Expression Viewer (FireBrowse)DCHS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54798
GTEX Portal (Tissue expression)DCHS2
Human Protein AtlasENSG00000197410-DCHS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6V1P9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6V1P9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6V1P9
Splice isoforms : SwissVarQ6V1P9
PhosPhoSitePlusQ6V1P9
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS   
Domain families : Pfam (Sanger)Cadherin (PF00028)   
Domain families : Pfam (NCBI)pfam00028   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)DCHS2
DMDM Disease mutations54798
Blocks (Seattle)DCHS2
SuperfamilyQ6V1P9
Human Protein Atlas [tissue]ENSG00000197410-DCHS2 [tissue]
Peptide AtlasQ6V1P9
IPIIPI00014829   IPI00896525   IPI01013679   IPI00915930   IPI00399257   
Protein Interaction databases
DIP (DOE-UCLA)Q6V1P9
IntAct (EBI)Q6V1P9
FunCoupENSG00000197410
BioGRIDDCHS2
STRING (EMBL)DCHS2
ZODIACDCHS2
Ontologies - Pathways
QuickGOQ6V1P9
Ontology : AmiGOmolecular_function  calcium ion binding  cellular_component  plasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  biological_process  integral component of membrane  cadherin binding  cell-cell adhesion  
Ontology : EGO-EBImolecular_function  calcium ion binding  cellular_component  plasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  biological_process  integral component of membrane  cadherin binding  cell-cell adhesion  
NDEx NetworkDCHS2
Atlas of Cancer Signalling NetworkDCHS2
Wikipedia pathwaysDCHS2
Orthology - Evolution
OrthoDB54798
GeneTree (enSembl)ENSG00000197410
Phylogenetic Trees/Animal Genes : TreeFamDCHS2
HOGENOMQ6V1P9
Homologs : HomoloGeneDCHS2
Homology/Alignments : Family Browser (UCSC)DCHS2
Gene fusions - Rearrangements
Fusion : QuiverDCHS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCHS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCHS2
dbVarDCHS2
ClinVarDCHS2
1000_GenomesDCHS2 
Exome Variant ServerDCHS2
ExAC (Exome Aggregation Consortium)ENSG00000197410
GNOMAD BrowserENSG00000197410
Varsome BrowserDCHS2
Genetic variants : HAPMAP54798
Genomic Variants (DGV)DCHS2 [DGVbeta]
DECIPHERDCHS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCHS2 
Mutations
ICGC Data PortalDCHS2 
TCGA Data PortalDCHS2 
Broad Tumor PortalDCHS2
OASIS PortalDCHS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCHS2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDCHS2
Mutations and Diseases : HGMDDCHS2
BioMutasearch DCHS2
DgiDB (Drug Gene Interaction Database)DCHS2
DoCM (Curated mutations)DCHS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCHS2 (select a term)
intoGenDCHS2
Cancer3DDCHS2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612486   
Orphanet
DisGeNETDCHS2
MedgenDCHS2
Genetic Testing Registry DCHS2
NextProtQ6V1P9 [Medical]
TSGene54798
GENETestsDCHS2
Target ValidationDCHS2
Huge Navigator DCHS2 [HugePedia]
snp3D : Map Gene to Disease54798
BioCentury BCIQDCHS2
ClinGenDCHS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54798
Chemical/Pharm GKB GenePA134953793
Clinical trialDCHS2
Miscellaneous
canSAR (ICR)DCHS2 (select the gene name)
DataMed IndexDCHS2
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCHS2
EVEXDCHS2
GoPubMedDCHS2
iHOPDCHS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:39:51 CET 2019
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