Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1638
MIM: 191275
HGNC: 2709
Ensembl: ENSG00000080166
Variants:
dbSNP: 1638
ClinVar: 1638
TCGA: ENSG00000080166
COSMIC: DCT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000080166 | ENST00000377028 | P40126 |
| ENSG00000080166 | ENST00000446125 | P40126 |
| ENSG00000080166 | ENST00000483392 | A0A0A0MTD3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35163231 | 2022 | Protein Biochemistry and Molecular Modeling of the Intra-Melanosomal Domain of Human Recombinant Tyrp2 Protein and OCA8-Related Mutant Variants. | 4 |
| 36274817 | 2022 | Dopachrome tautomerase is a retinoblastoma-specific gene, and its proximal promoter is preferentially active in human retinoblastoma cells. | 1 |
| 35163231 | 2022 | Protein Biochemistry and Molecular Modeling of the Intra-Melanosomal Domain of Human Recombinant Tyrp2 Protein and OCA8-Related Mutant Variants. | 4 |
| 36274817 | 2022 | Dopachrome tautomerase is a retinoblastoma-specific gene, and its proximal promoter is preferentially active in human retinoblastoma cells. | 1 |
| 33314655 | 2021 | Evaluation of the effect of narrow band-ultraviolet B on the expression of tyrosinase, TYRP-1, and TYRP-2 mRNA in vitiligo skin and their correlations with clinical improvement: A retrospective study. | 4 |
| 33959807 | 2021 | Biallelic mutations in L-dopachrome tautomerase (DCT) cause infantile nystagmus and oculocutaneous albinism. | 9 |
| 34107850 | 2021 | Identification of TYR, TYRP1, DCT and LARP7 as related biomarkers and immune infiltration characteristics of vitiligo via comprehensive strategies. | 13 |
| 33314655 | 2021 | Evaluation of the effect of narrow band-ultraviolet B on the expression of tyrosinase, TYRP-1, and TYRP-2 mRNA in vitiligo skin and their correlations with clinical improvement: A retrospective study. | 4 |
| 33959807 | 2021 | Biallelic mutations in L-dopachrome tautomerase (DCT) cause infantile nystagmus and oculocutaneous albinism. | 9 |
| 34107850 | 2021 | Identification of TYR, TYRP1, DCT and LARP7 as related biomarkers and immune infiltration characteristics of vitiligo via comprehensive strategies. | 13 |
| 31208857 | 2019 | Transcriptional repression of the tyrosinase-related protein 2 gene by transforming growth factor-β and the Kruppel-like transcription factor GLI2. | 3 |
| 31208857 | 2019 | Transcriptional repression of the tyrosinase-related protein 2 gene by transforming growth factor-β and the Kruppel-like transcription factor GLI2. | 3 |
| 28095444 | 2017 | The Role of DCT in HPV16 Infection of HaCaTs. | 10 |
| 28923927 | 2017 | MIF and D-DT are potential disease severity modifiers in male MS subjects. | 51 |
| 28095444 | 2017 | The Role of DCT in HPV16 Infection of HaCaTs. | 10 |
Citation
Dessen P
DCT (dopachrome tautomerase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43594/dct
