Identity
HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
DCTN50,DYNAMITIN,HEL-S-77,RBP50
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10540
MIM: 607376
HGNC: 2712
Ensembl: ENSG00000175203
Variants:
dbSNP: 10540
ClinVar: 10540
TCGA: ENSG00000175203
COSMIC: DCTN2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38842133 | 2024 | Pan-cancer analysis of DCTN2 and its tumour-promoting role in HCC by modulating the AKT pathway. | 1 |
| 38842133 | 2024 | Pan-cancer analysis of DCTN2 and its tumour-promoting role in HCC by modulating the AKT pathway. | 1 |
| 34080666 | 2021 | Binding between ROCK1 and DCTN2 triggers diabetes‑associated centrosome amplification in colon cancer cells. | 2 |
| 34080666 | 2021 | Binding between ROCK1 and DCTN2 triggers diabetes‑associated centrosome amplification in colon cancer cells. | 2 |
| 26517670 | 2016 | Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot-Marie-Tooth disease in a Norwegian family. | 7 |
| 26517670 | 2016 | Variants in the genes DCTN2, DNAH10, LRIG3, and MYO1A are associated with intermediate Charcot-Marie-Tooth disease in a Norwegian family. | 7 |
| 25088759 | 2014 | Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5. | 7 |
| 25088759 | 2014 | Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5. | 7 |
| 20463029 | 2010 | Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex. | 11 |
| 20463029 | 2010 | Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex. | 11 |
| 18182012 | 2008 | Dynamitin mutagenesis reveals protein-protein interactions important for dynactin structure. | 12 |
| 18782227 | 2008 | N-terminal region of ZW10 serves not only as a determinant for localization but also as a link with dynein function. | 7 |
| 18182012 | 2008 | Dynamitin mutagenesis reveals protein-protein interactions important for dynactin structure. | 12 |
| 18782227 | 2008 | N-terminal region of ZW10 serves not only as a determinant for localization but also as a link with dynein function. | 7 |
| 16369996 | 2006 | Phenotypic changes associated with DYNACTIN-2 (DCTN2) over expression characterise SJSA-1 osteosarcoma cells. | 8 |
Citation
Dessen P
DCTN2 (dynactin subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43939/dctn2
