DCTN6 (dynactin subunit 6)

2001-01-01  

Identity

HGNC
LOCATION
8p12
LOCUSID
ALIAS
WS-3,WS3,p27
FUSION GENES

Other Information

Locus ID:

NCBI: 10671
MIM: 612963
HGNC: 16964
Ensembl: ENSG00000104671

Variants:

dbSNP: 10671
ClinVar: 10671
TCGA: ENSG00000104671
COSMIC: DCTN6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104671ENST00000221114O00399
ENSG00000104671ENST00000519830E5RIK5
ENSG00000104671ENST00000520829E5RK00
ENSG00000104671ENST00000522141E5RGW9
ENSG00000104671ENST00000523666E5RFU3

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-independent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811436

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
234551522013Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.21

Citation

Dessen P

DCTN6 (dynactin subunit 6)

Atlas Genet Cytogenet Oncol Haematol. 2001-01-01

Online version: http://atlasgeneticsoncology.org/gene/78518/dctn6