Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DCX (doublecortin)

Identity

Alias (NCBI)DBCN
DC
LISX
SCLH
XLIS
HGNC (Hugo) DCX
HGNC Alias symbSCLH
DC
LISX
DBCN
XLIS
HGNC Alias namedoublecortex
HGNC Previous namedoublecortex; lissencephaly, X-linked (doublecortin)
LocusID (NCBI) 1641
Atlas_Id 45751
Location Xq23  [Link to chromosome band Xq23]
Location_base_pair Starts at 111293779 and ends at 111412192 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAPN6 (Xq23) / DCX (Xq23)DCX (Xq23) / PASD1 (Xq28)ZNF785 (16p11.2) / DCX (Xq23)
CAPN6 Xq23 / DCX Xq23DCX Xq23 / PASD1 Xq28

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)DCX   2714
Cards
Entrez_Gene (NCBI)DCX  1641  doublecortin
AliasesDBCN; DC; LISX; SCLH; 
XLIS
GeneCards (Weizmann)DCX
Ensembl hg19 (Hinxton)ENSG00000077279 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077279 [Gene_View]  ENSG00000077279 [Sequence]  chrX:111293779-111412192 [Contig_View]  DCX [Vega]
ICGC DataPortalENSG00000077279
TCGA cBioPortalDCX
AceView (NCBI)DCX
Genatlas (Paris)DCX
WikiGenes1641
SOURCE (Princeton)DCX
Genetics Home Reference (NIH)DCX
Genomic and cartography
GoldenPath hg38 (UCSC)DCX  -     chrX:111293779-111412192 -  Xq23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCX  -     Xq23   [Description]    (hg19-Feb_2009)
GoldenPathDCX - Xq23 [CytoView hg19]  DCX - Xq23 [CytoView hg38]
ImmunoBaseENSG00000077279
genome Data Viewer NCBIDCX [Mapview hg19]  
OMIM300067   300121   
Gene and transcription
Genbank (Entrez)AF034634 AF040254 AF040255 AJ003112 AK002120
RefSeq transcript (Entrez)NM_000555 NM_001195553 NM_001369370 NM_001369371 NM_001369372 NM_001369373 NM_001369374 NM_178151 NM_178152 NM_178153
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCX
Alternative Splicing GalleryENSG00000077279
Gene ExpressionDCX [ NCBI-GEO ]   DCX [ EBI - ARRAY_EXPRESS ]   DCX [ SEEK ]   DCX [ MEM ]
Gene Expression Viewer (FireBrowse)DCX [ Firebrowse - Broad ]
GenevisibleExpression of DCX in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1641
GTEX Portal (Tissue expression)DCX
Human Protein AtlasENSG00000077279-DCX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43602   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43602  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43602
Splice isoforms : SwissVarO43602
PhosPhoSitePlusO43602
Domaine pattern : Prosite (Expaxy)DC (PS50309)   
Domains : Interpro (EBI)Doublecortin_chordata    Doublecortin_dom    Doublecortin_dom_sf    RP1/RP1L1/DCX   
Domain families : Pfam (Sanger)DCX (PF03607)   
Domain families : Pfam (NCBI)pfam03607   
Domain families : Smart (EMBL)DCX (SM00537)  
Conserved Domain (NCBI)DCX
DMDM Disease mutations1641
Blocks (Seattle)DCX
PDB (RSDB)1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
PDB Europe1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
PDB (PDBSum)1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
PDB (IMB)1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
Structural Biology KnowledgeBase1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
SCOP (Structural Classification of Proteins)1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
CATH (Classification of proteins structures)1MJD    2BQQ    2XRP    4ATU    5IKC    5IN7    5IO9    5IOI    5IP4    6FNZ   
SuperfamilyO43602
Human Protein Atlas [tissue]ENSG00000077279-DCX [tissue]
Peptide AtlasO43602
HPRD02127
IPIIPI00216744   IPI00220076   IPI00220077   IPI00220078   IPI00847840   IPI00946204   IPI00982341   IPI00945328   
Protein Interaction databases
DIP (DOE-UCLA)O43602
IntAct (EBI)O43602
FunCoupENSG00000077279
BioGRIDDCX
STRING (EMBL)DCX
ZODIACDCX
Ontologies - Pathways
QuickGOO43602
Ontology : AmiGOneuron migration  protein binding  cytosol  cytoskeleton  microtubule  microtubule associated complex  axoneme  nervous system development  central nervous system development  microtubule binding  microtubule binding  protein kinase binding  axoneme assembly  intracellular signal transduction  photoreceptor cell development  neuron projection  retina development in camera-type eye  
Ontology : EGO-EBIneuron migration  protein binding  cytosol  cytoskeleton  microtubule  microtubule associated complex  axoneme  nervous system development  central nervous system development  microtubule binding  microtubule binding  protein kinase binding  axoneme assembly  intracellular signal transduction  photoreceptor cell development  neuron projection  retina development in camera-type eye  
NDEx NetworkDCX
Atlas of Cancer Signalling NetworkDCX
Wikipedia pathwaysDCX
Orthology - Evolution
OrthoDB1641
GeneTree (enSembl)ENSG00000077279
Phylogenetic Trees/Animal Genes : TreeFamDCX
HOGENOMO43602
Homologs : HomoloGeneDCX
Homology/Alignments : Family Browser (UCSC)DCX
Gene fusions - Rearrangements
Fusion PortalCAPN6 Xq23 DCX Xq23 BRCA
Fusion PortalDCX Xq23 PASD1 Xq28 KIRC
Fusion : QuiverDCX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCX
dbVarDCX
ClinVarDCX
MonarchDCX
1000_GenomesDCX 
Exome Variant ServerDCX
GNOMAD BrowserENSG00000077279
Varsome BrowserDCX
Genetic variants : HAPMAP1641
Genomic Variants (DGV)DCX [DGVbeta]
DECIPHERDCX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCX 
Mutations
ICGC Data PortalDCX 
TCGA Data PortalDCX 
Broad Tumor PortalDCX
OASIS PortalDCX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCX  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDCX
Mutations and Diseases : HGMDDCX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DCX
DgiDB (Drug Gene Interaction Database)DCX
DoCM (Curated mutations)DCX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCX (select a term)
intoGenDCX
Cancer3DDCX(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300067    300121   
Orphanet2047    14369   
DisGeNETDCX
MedgenDCX
Genetic Testing Registry DCX
NextProtO43602 [Medical]
TSGene1641
GENETestsDCX
Target ValidationDCX
Huge Navigator DCX [HugePedia]
snp3D : Map Gene to Disease1641
BioCentury BCIQDCX
ClinGenDCX (curated)
Clinical trials, drugs, therapy
Protein Interactions : CTD1641
Pharm GKB GenePA27184
Clinical trialDCX
Miscellaneous
canSAR (ICR)DCX (select the gene name)
HarmonizomeDCX
DataMed IndexDCX
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCX
EVEXDCX
GoPubMedDCX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:08:21 CEST 2020

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