Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DDX55 (DEAD-box helicase 55)

Identity

Alias_namesDEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Alias_symbol (synonym)KIAA1595
Other alias-
HGNC (Hugo) DDX55
LocusID (NCBI) 57696
Atlas_Id 46960
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 123602077 and ends at 123620943 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CACNA1C (12p13.33) / DDX55 (12q24.31)DDX55 (12q24.31) / ALDH3A1 (17p11.2)GTF2H3 (12q24.31) / DDX55 (12q24.31)
CACNA1C 12p13.33 / DDX55 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(12;12)(p13;q24) CACNA1C/DDX55
GTF2H3/DDX55 (12q24)

External links

Nomenclature
HGNC (Hugo)DDX55   20085
Cards
Entrez_Gene (NCBI)DDX55  57696  DEAD-box helicase 55
Aliases
GeneCards (Weizmann)DDX55
Ensembl hg19 (Hinxton)ENSG00000111364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111364 [Gene_View]  ENSG00000111364 [Sequence]  chr12:123602077-123620943 [Contig_View]  DDX55 [Vega]
ICGC DataPortalENSG00000111364
TCGA cBioPortalDDX55
AceView (NCBI)DDX55
Genatlas (Paris)DDX55
WikiGenes57696
SOURCE (Princeton)DDX55
Genetics Home Reference (NIH)DDX55
Genomic and cartography
GoldenPath hg38 (UCSC)DDX55  -     chr12:123602077-123620943 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX55  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathDDX55 - 12q24.31 [CytoView hg19]  DDX55 - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000111364
Mapping of homologs : NCBIDDX55 [Mapview hg19]  DDX55 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA403154 AB046815 AK074219 AK131442 AK301043
RefSeq transcript (Entrez)NM_020936
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX55
Cluster EST : UnigeneHs.286173 [ NCBI ]
CGAP (NCI)Hs.286173
Alternative Splicing GalleryENSG00000111364
Gene ExpressionDDX55 [ NCBI-GEO ]   DDX55 [ EBI - ARRAY_EXPRESS ]   DDX55 [ SEEK ]   DDX55 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX55 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57696
GTEX Portal (Tissue expression)DDX55
Human Protein AtlasENSG00000111364-DDX55 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHQ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHQ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHQ9
Splice isoforms : SwissVarQ8NHQ9
PhosPhoSitePlusQ8NHQ9
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DUF4217    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    DUF4217 (PF13959)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam13959    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  DUF4217 (SM01178)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX55
DMDM Disease mutations57696
Blocks (Seattle)DDX55
SuperfamilyQ8NHQ9
Human Protein Atlas [tissue]ENSG00000111364-DDX55 [tissue]
Peptide AtlasQ8NHQ9
HPRD13130
IPIIPI00185361   IPI00657777   IPI01018972   IPI01011157   IPI01010798   IPI01010332   IPI00791512   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHQ9
IntAct (EBI)Q8NHQ9
FunCoupENSG00000111364
BioGRIDDDX55
STRING (EMBL)DDX55
ZODIACDDX55
Ontologies - Pathways
QuickGOQ8NHQ9
Ontology : AmiGORNA binding  RNA binding  RNA helicase activity  RNA helicase activity  protein binding  ATP binding  nucleus  nucleolus  nucleolus  cytosol  membrane  
Ontology : EGO-EBIRNA binding  RNA binding  RNA helicase activity  RNA helicase activity  protein binding  ATP binding  nucleus  nucleolus  nucleolus  cytosol  membrane  
NDEx NetworkDDX55
Atlas of Cancer Signalling NetworkDDX55
Wikipedia pathwaysDDX55
Orthology - Evolution
OrthoDB57696
GeneTree (enSembl)ENSG00000111364
Phylogenetic Trees/Animal Genes : TreeFamDDX55
HOGENOMQ8NHQ9
Homologs : HomoloGeneDDX55
Homology/Alignments : Family Browser (UCSC)DDX55
Gene fusions - Rearrangements
Fusion : MitelmanCACNA1C/DDX55 [12p13.33/12q24.31]  [t(12;12)(p13;q24)]  
Fusion : MitelmanGTF2H3/DDX55 [12q24.31/12q24.31]  [t(12;12)(q24;q24)]  
Fusion PortalCACNA1C 12p13.33 DDX55 12q24.31 PRAD
Fusion : QuiverDDX55
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX55 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX55
dbVarDDX55
ClinVarDDX55
1000_GenomesDDX55 
Exome Variant ServerDDX55
ExAC (Exome Aggregation Consortium)ENSG00000111364
GNOMAD BrowserENSG00000111364
Varsome BrowserDDX55
Genetic variants : HAPMAP57696
Genomic Variants (DGV)DDX55 [DGVbeta]
DECIPHERDDX55 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX55 
Mutations
ICGC Data PortalDDX55 
TCGA Data PortalDDX55 
Broad Tumor PortalDDX55
OASIS PortalDDX55 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX55  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDDX55
Mutations and Diseases : HGMDDDX55
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDX55
DgiDB (Drug Gene Interaction Database)DDX55
DoCM (Curated mutations)DDX55 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX55 (select a term)
intoGenDDX55
Cancer3DDDX55(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETDDX55
MedgenDDX55
Genetic Testing Registry DDX55
NextProtQ8NHQ9 [Medical]
TSGene57696
GENETestsDDX55
Target ValidationDDX55
Huge Navigator DDX55 [HugePedia]
snp3D : Map Gene to Disease57696
BioCentury BCIQDDX55
ClinGenDDX55
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57696
Chemical/Pharm GKB GenePA134984021
Clinical trialDDX55
Miscellaneous
canSAR (ICR)DDX55 (select the gene name)
DataMed IndexDDX55
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX55
EVEXDDX55
GoPubMedDDX55
iHOPDDX55
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:40:05 CET 2019
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