Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1669
MIM: 601157
HGNC: 2763
Ensembl: ENSG00000164821
Variants:
dbSNP: 1669
ClinVar: 1669
TCGA: ENSG00000164821
COSMIC: DEFA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164821 | ENST00000297435 | P12838 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30658057 | 2019 | Systematic mutational analysis of human neutrophil α-defensin HNP4. | 6 |
| 30658057 | 2019 | Systematic mutational analysis of human neutrophil α-defensin HNP4. | 6 |
| 29446150 | 2018 | Antimicrobial peptide gene expression in periodontitis patients: A pilot study. | 6 |
| 29446150 | 2018 | Antimicrobial peptide gene expression in periodontitis patients: A pilot study. | 6 |
| 23050799 | 2012 | Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours. | 9 |
| 23050799 | 2012 | Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours. | 9 |
| 21734341 | 2011 | α-defensin 1-3 and α-defensin 4 as predictive markers of imatinib resistance and relapse in CML patients. | 2 |
| 21734341 | 2011 | α-defensin 1-3 and α-defensin 4 as predictive markers of imatinib resistance and relapse in CML patients. | 2 |
| 20016407 | 2010 | Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations. | 5 |
| 20056178 | 2010 | Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. | 6 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20406964 | 2010 | Risk of meningioma and common variation in genes related to innate immunity. | 21 |
| 20438785 | 2010 | Polymorphisms in innate immunity genes and risk of childhood leukemia. | 12 |
| 20727496 | 2010 | Gene expression of oncogenes, antimicrobial peptides, and cytokines in the development of oral leukoplakia. | 11 |
| 20016407 | 2010 | Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations. | 5 |
Citation
Dessen P
DEFA4 (defensin alpha 4)
Atlas Genet Cytogenet Oncol Haematol. 2011-02-01
Online version: http://atlasgeneticsoncology.org/gene/52075/defa4
