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DEFB105B (defensin beta 105B)

Identity

Alias_namesdefensin, beta 105B
Other aliasBD-5
DEFB-5
HGNC (Hugo) DEFB105B
LocusID (NCBI) 504180
Atlas_Id 62388
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 7487669 and ends at 7489593 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DEFB105B   29930
Cards
Entrez_Gene (NCBI)DEFB105B  504180  defensin beta 105B
AliasesBD-5; DEFB-5
GeneCards (Weizmann)DEFB105B
Ensembl hg19 (Hinxton)ENSG00000186599 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186599 [Gene_View]  ENSG00000186599 [Sequence]  chr8:7487669-7489593 [Contig_View]  DEFB105B [Vega]
ICGC DataPortalENSG00000186599
TCGA cBioPortalDEFB105B
AceView (NCBI)DEFB105B
Genatlas (Paris)DEFB105B
WikiGenes504180
SOURCE (Princeton)DEFB105B
Genetics Home Reference (NIH)DEFB105B
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB105B  -     chr8:7487669-7489593 +  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB105B  -     8p23.1   [Description]    (hg19-Feb_2009)
GoldenPathDEFB105B - 8p23.1 [CytoView hg19]  DEFB105B - 8p23.1 [CytoView hg38]
ImmunoBaseENSG00000186599
Mapping of homologs : NCBIDEFB105B [Mapview hg19]  DEFB105B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB089180 AF540977 BC128437 BC128438 BC140937
RefSeq transcript (Entrez)NM_001040703
RefSeq genomic (Entrez)NC_000008 NT_187570 NW_018654717
Consensus coding sequences : CCDS (NCBI)DEFB105B
Cluster EST : UnigeneHs.381378 [ NCBI ]
CGAP (NCI)Hs.381378
Alternative Splicing GalleryENSG00000186599
Gene ExpressionDEFB105B [ NCBI-GEO ]   DEFB105B [ EBI - ARRAY_EXPRESS ]   DEFB105B [ SEEK ]   DEFB105B [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB105B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)504180
GTEX Portal (Tissue expression)DEFB105B
Human Protein AtlasENSG00000186599-DEFB105B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NG35   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NG35  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NG35
Splice isoforms : SwissVarQ8NG35
PhosPhoSitePlusQ8NG35
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Conserved Domain (NCBI)DEFB105B
DMDM Disease mutations504180
Blocks (Seattle)DEFB105B
SuperfamilyQ8NG35
Human Protein Atlas [tissue]ENSG00000186599-DEFB105B [tissue]
Peptide AtlasQ8NG35
Protein Interaction databases
DIP (DOE-UCLA)Q8NG35
IntAct (EBI)Q8NG35
FunCoupENSG00000186599
BioGRIDDEFB105B
STRING (EMBL)DEFB105B
ZODIACDEFB105B
Ontologies - Pathways
QuickGOQ8NG35
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB105B
Atlas of Cancer Signalling NetworkDEFB105B
Wikipedia pathwaysDEFB105B
Orthology - Evolution
OrthoDB504180
GeneTree (enSembl)ENSG00000186599
Phylogenetic Trees/Animal Genes : TreeFamDEFB105B
HOGENOMQ8NG35
Homologs : HomoloGeneDEFB105B
Homology/Alignments : Family Browser (UCSC)DEFB105B
Gene fusions - Rearrangements
Fusion : QuiverDEFB105B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB105B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB105B
dbVarDEFB105B
ClinVarDEFB105B
1000_GenomesDEFB105B 
Exome Variant ServerDEFB105B
ExAC (Exome Aggregation Consortium)ENSG00000186599
GNOMAD BrowserENSG00000186599
Varsome BrowserDEFB105B
Genetic variants : HAPMAP504180
Genomic Variants (DGV)DEFB105B [DGVbeta]
DECIPHERDEFB105B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB105B 
Mutations
ICGC Data PortalDEFB105B 
TCGA Data PortalDEFB105B 
Broad Tumor PortalDEFB105B
OASIS PortalDEFB105B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB105B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDEFB105B
Mutations and Diseases : HGMDDEFB105B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB105B
DgiDB (Drug Gene Interaction Database)DEFB105B
DoCM (Curated mutations)DEFB105B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB105B (select a term)
intoGenDEFB105B
Cancer3DDEFB105B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETDEFB105B
MedgenDEFB105B
Genetic Testing Registry DEFB105B
NextProtQ8NG35 [Medical]
TSGene504180
GENETestsDEFB105B
Target ValidationDEFB105B
Huge Navigator DEFB105B [HugePedia]
snp3D : Map Gene to Disease504180
BioCentury BCIQDEFB105B
ClinGenDEFB105B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD504180
Chemical/Pharm GKB GenePA142671991
Clinical trialDEFB105B
Miscellaneous
canSAR (ICR)DEFB105B (select the gene name)
DataMed IndexDEFB105B
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB105B
EVEXDEFB105B
GoPubMedDEFB105B
iHOPDEFB105B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:25:26 CEST 2019
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