DEPDC7 (DEP domain containing 7)

2018-07-01  

Identity

HGNC
LOCATION
11p13
LOCUSID
ALIAS
TR2,dJ85M6.4

Other Information

Locus ID:

NCBI: 91614
MIM: 612294
HGNC: 29899
Ensembl: ENSG00000121690

Variants:

dbSNP: 91614
ClinVar: 91614
TCGA: ENSG00000121690
COSMIC: DEPDC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121690ENST00000241051Q96QD5
ENSG00000121690ENST00000311388Q96QD5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

References

Pubmed IDYearTitleCitations
255419732014The Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing protein DEPDC7 binds to CARMA2 and CARMA3 proteins, and regulates NF-κB activation.12
259521352015Further evidence of DEPDC7 DNA hypomethylation in depression: A study in adult twins.4
270162542017Construction and Identification of the RNAi Recombinant Lentiviral Vector Targeting Human DEPDC7 Gene.3

Citation

Dessen P

DEPDC7 (DEP domain containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57412/depdc7