Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1677
MIM: 601883
HGNC: 2773
Ensembl: ENSG00000169598
Variants:
dbSNP: 1677
ClinVar: 1677
TCGA: ENSG00000169598
COSMIC: DFFB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37215747 | 2023 | MEG3 Regulates CSE-Induced Apoptosis by Regulating miR-421/DFFB Signal Axis. | 0 |
| 37215747 | 2023 | MEG3 Regulates CSE-Induced Apoptosis by Regulating miR-421/DFFB Signal Axis. | 0 |
| 35393399 | 2022 | Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. | 8 |
| 35393399 | 2022 | Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. | 8 |
| 33387146 | 2021 | The role of the DFF40/CAD endonuclease in genomic stability. | 2 |
| 34006390 | 2021 | The Nexus of cfDNA and Nuclease Biology. | 51 |
| 34678222 | 2021 | DFF40 deficiency in cancerous T cells is implicated in chemotherapy drug sensitivity and resistance through the regulation of the apoptotic pathway. | 1 |
| 33387146 | 2021 | The role of the DFF40/CAD endonuclease in genomic stability. | 2 |
| 34006390 | 2021 | The Nexus of cfDNA and Nuclease Biology. | 51 |
| 34678222 | 2021 | DFF40 deficiency in cancerous T cells is implicated in chemotherapy drug sensitivity and resistance through the regulation of the apoptotic pathway. | 1 |
| 28914671 | 2018 | Endometrial Polyps and Benign Endometrial Hyperplasia Have Increased Prevalence of DNA Fragmentation Factors 40 and 45 (DFF40 and DFF45) Together With the Antiapoptotic B-Cell Lymphoma (Bcl-2) Protein Compared With Normal Human Endometria. | 2 |
| 28914671 | 2018 | Endometrial Polyps and Benign Endometrial Hyperplasia Have Increased Prevalence of DNA Fragmentation Factors 40 and 45 (DFF40 and DFF45) Together With the Antiapoptotic B-Cell Lymphoma (Bcl-2) Protein Compared With Normal Human Endometria. | 2 |
| 28981092 | 2017 | Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. | 18 |
| 28981092 | 2017 | Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. | 18 |
| 26755073 | 2016 | An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells. | 8 |
Citation
Dessen P
DFFB (DNA fragmentation factor subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40298/dffb
