DHX37 (DEAH-box helicase 37)

2007-04-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
DDX37,Dhr1,NEDBAVC,SRXY11
FUSION GENES

Other Information

Locus ID:

NCBI: 57647
MIM: 617362
HGNC: 17210
Ensembl: ENSG00000150990

Variants:

dbSNP: 57647
ClinVar: 57647
TCGA: ENSG00000150990
COSMIC: DHX37

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150990ENST00000308736Q8IY37
ENSG00000150990ENST00000544745F5H3Y4

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
312875412019Genetic Evidence of the Association of DEAH-Box Helicase 37 Defects With 46,XY Gonadal Dysgenesis Spectrum.4
313378832020Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome.4

Citation

Dessen P

DHX37 (DEAH-box helicase 37)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47074/dhx37