Identity
HGNC
LOCATION
13q21.2
LOCUSID
ALIAS
AN,AUNA1,DIA2,DRF3,NSDAN,diap3,mDia2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81624
MIM: 614567
HGNC: 15480
Ensembl: ENSG00000139734
Variants:
dbSNP: 81624
ClinVar: 81624
TCGA: ENSG00000139734
COSMIC: DIAPH3
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447288 | Essential hypertension | Disease | ClinicalAnnotation | associated | PD | ||
| PA449899 | hydrochlorothiazide | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38613636 | 2024 | CircDiaph3 aggravates H/R-induced cardiomyocyte apoptosis and inflammation through miR-338-3p/SRSF1 axis. | 0 |
| 38613636 | 2024 | CircDiaph3 aggravates H/R-induced cardiomyocyte apoptosis and inflammation through miR-338-3p/SRSF1 axis. | 0 |
| 36640348 | 2023 | DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling. | 5 |
| 36750200 | 2023 | The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer. | 1 |
| 37756562 | 2023 | Super Enhancer-Regulated LncRNA LINC01089 Induces Alternative Splicing of DIAPH3 to Drive Hepatocellular Carcinoma Metastasis. | 4 |
| 36640348 | 2023 | DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling. | 5 |
| 36750200 | 2023 | The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer. | 1 |
| 37756562 | 2023 | Super Enhancer-Regulated LncRNA LINC01089 Induces Alternative Splicing of DIAPH3 to Drive Hepatocellular Carcinoma Metastasis. | 4 |
| 35380294 | 2022 | Diaph3 underlines tumor cell heterogeneity in glioblastoma with implications for treatment modalities resistance. | 1 |
| 35538918 | 2022 | DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation. | 1 |
| 35380294 | 2022 | Diaph3 underlines tumor cell heterogeneity in glioblastoma with implications for treatment modalities resistance. | 1 |
| 35538918 | 2022 | DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation. | 1 |
| 33345387 | 2021 | DIAPH3 promotes pancreatic cancer progression by activating selenoprotein TrxR1-mediated antioxidant effects. | 20 |
| 33345387 | 2021 | DIAPH3 promotes pancreatic cancer progression by activating selenoprotein TrxR1-mediated antioxidant effects. | 20 |
| 33297976 | 2020 | Novel stromal biomarker screening in pancreatic cancer patients using the in vitro cancer-stromal interaction model. | 1 |
Citation
Dessen P
DIAPH3 (diaphanous related formin 3)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53110/diaph3
