Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1735
MIM: 601038
HGNC: 2885
Ensembl: ENSG00000197406
Variants:
dbSNP: 1735
ClinVar: 1735
TCGA: ENSG00000197406
COSMIC: DIO3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197406 | ENST00000510508 | P55073 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38311851 | 2024 | DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis. | 1 |
| 38609422 | 2024 | MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity. | 0 |
| 38659084 | 2024 | Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression. | 0 |
| 38311851 | 2024 | DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis. | 1 |
| 38609422 | 2024 | MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity. | 0 |
| 38659084 | 2024 | Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression. | 0 |
| 36907530 | 2023 | Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development. | 0 |
| 37116683 | 2023 | MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity. | 0 |
| 36907530 | 2023 | Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development. | 0 |
| 37116683 | 2023 | MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity. | 0 |
| 32977740 | 2021 | Downregulation of Caveolin-1 and Upregulation of Deiodinase 3, Associated with Hypoxia-Inducible Factor-1α Increase, Are Involved in the Oxidative Stress of Graves' Orbital Adipocytes. | 6 |
| 33221455 | 2021 | DIO3, the thyroid hormone inactivating enzyme, promotes tumorigenesis and metabolic reprogramming in high grade serous ovarian cancer. | 5 |
| 33720335 | 2021 | Deiodinases and the Metabolic Code for Thyroid Hormone Action. | 29 |
| 34129219 | 2021 | Loss of Selenoprotein Iodothyronine Deiodinase 3 Expression Correlates with Progression of Complete Hydatidiform Mole to Gestational Trophoblastic Neoplasia. | 1 |
| 34294738 | 2021 | Human placental piwi-interacting RNA transcriptome is characterized by expression from the DLK1-DIO3 imprinted region. | 4 |
Citation
Dessen P
DIO3 (iodothyronine deiodinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40309/dio3
