DIRAS1 (DIRAS family GTPase 1)

2003-02-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
Di-Ras1,GBTS1,RIG

Other Information

Locus ID:

NCBI: 148252
MIM: 607862
HGNC: 19127
Ensembl: ENSG00000176490

Variants:

dbSNP: 148252
ClinVar: 148252
TCGA: ENSG00000176490
COSMIC: DIRAS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176490ENST00000323469O95057
ENSG00000176490ENST00000585334O95057
ENSG00000176490ENST00000588128K7EN06

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
234368002013Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.24
121072782002Rig is a novel Ras-related protein and potential neural tumor suppressor.16
268141302016The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases.8
282235332017Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1.6
284911512017Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis.6

Citation

Dessen P

DIRAS1 (DIRAS family GTPase 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40310/diras1