DLG5 (discs large MAGUK scaffold protein 5)

2003-06-01  

Identity

HGNC
LOCATION
10q22.3
LOCUSID
ALIAS
LP-DLG,P-DLG5,PDLG
FUSION GENES

Other Information

Locus ID:

NCBI: 9231
MIM: 604090
HGNC: 2904
Ensembl: ENSG00000151208

Variants:

dbSNP: 9231
ClinVar: 9231
TCGA: ENSG00000151208
COSMIC: DLG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151208ENST00000372391Q8TDM6
ENSG00000151208ENST00000424842A0A0A0MSL1
ENSG00000151208ENST00000468332R4GMQ2

Expression (GTEx)

0
10
20
30
40
50
60

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA128406956fluorouracilChemicalClinicalAnnotationassociatedPD
PA445058Neoplasm MetastasisDiseaseClinicalAnnotationassociatedPD
PA448771capecitabineChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
151078522004Genetic variation in DLG5 is associated with inflammatory bowel disease.93
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
188245552009Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort.48
156652852005Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.42
175440132007Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer.34
159557862005Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.33
194229352009Genetic risk profiling and prediction of disease course in Crohn's disease patients.33
174766802007Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.32
174766802007Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.32

Citation

Dessen P

DLG5 (discs large MAGUK scaffold protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40335/dlg5