DLGAP2 (DLG associated protein 2)

2017-04-01 Affiliation

Identity

HGNC

DLGAP2

LOCATION

8p23.3

LOCUSID

9228

ALIAS

C8orf68,DAP2,ERICH1-AS1,SAPAP2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9228
MIM: 605438
HGNC: 2906
Ensembl: ENSG00000198010

Variants:

dbSNP: 9228
ClinVar: 9228
TCGA: ENSG00000198010
COSMIC: DLGAP2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000198010	ENST00000421627	Q9P1A6
ENSG00000198010	ENST00000518530	A0A0J9YWL8
ENSG00000198010	ENST00000520901	H0YBY6
ENSG00000198010	ENST00000522499	A0A0J9YY16
ENSG00000198010	ENST00000612087	A0A1B0GXK6
ENSG00000198010	ENST00000637795	A0A1B0GTN4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Neuronal System	REACTOME	R-HSA-112316
Protein-protein interactions at synapses	REACTOME	R-HSA-6794362
Interactions of neurexins and neuroligins at synapses	REACTOME	R-HSA-6794361

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
20531469	2010	Functional impact of global rare copy number variation in autism spectrum disorders.	778
19736351	2009	Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.	151
18055845	2007	Computational and experimental identification of novel human imprinted genes.	139
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
26393913	2015	Three circulating long non-coding RNAs act as biomarkers for predicting NSCLC.	16
15030493	2004	Increased numbers of coassembled PSD-95 to NMDA-receptor subunits NR2B and NR1 in human epileptic cortical dysplasia.	15
23154099	2013	Glutamate system genes and brain volume alterations in pediatric obsessive-compulsive disorder: a preliminary study.	15
24416398	2014	Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.	13
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11

Citation

Dessen P

DLGAP2 (DLG associated protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56805/dlgap2