Identity
HGNC
LOCATION
14q32.2
LOCUSID
ALIAS
DLK,DLK-1,Delta1,FA1,PREF1,Pref-1,ZOG,pG2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8788
MIM: 176290
HGNC: 2907
Ensembl: ENSG00000185559
Variants:
dbSNP: 8788
ClinVar: 8788
TCGA: ENSG00000185559
COSMIC: DLK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185559 | ENST00000331224 | P80370 |
| ENSG00000185559 | ENST00000341267 | P80370 |
| ENSG00000185559 | ENST00000392848 | G3XAH5 |
| ENSG00000185559 | ENST00000556051 | G3V2R7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38185550 | 2024 | Exploring the role of DLK1 in inducing NLRP3 inflammasome activation in bladder epithelial cells in patients with interstitial cystitis. | 0 |
| 38311851 | 2024 | DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis. | 1 |
| 38328889 | 2024 | Pericardial delta like non-canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition. | 2 |
| 38609422 | 2024 | MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity. | 0 |
| 38185550 | 2024 | Exploring the role of DLK1 in inducing NLRP3 inflammasome activation in bladder epithelial cells in patients with interstitial cystitis. | 0 |
| 38311851 | 2024 | DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis. | 1 |
| 38328889 | 2024 | Pericardial delta like non-canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition. | 2 |
| 38609422 | 2024 | MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity. | 0 |
| 36577869 | 2023 | A new DLK1 defect in a family with idiopathic central precocious puberty: elucidation of the male phenotype. | 3 |
| 36907530 | 2023 | Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development. | 0 |
| 37703313 | 2023 | Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels. | 0 |
| 36577869 | 2023 | A new DLK1 defect in a family with idiopathic central precocious puberty: elucidation of the male phenotype. | 3 |
| 36907530 | 2023 | Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development. | 0 |
| 37703313 | 2023 | Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels. | 0 |
| 34606325 | 2022 | Emerging Roles of DLK1 in the Stem Cell Niche and Cancer Stemness. | 9 |
Citation
Dessen P
DLK1 (delta like non-canonical Notch ligand 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46393/dlk1
