Identity
HGNC
LOCATION
6q27
LOCUSID
ALIAS
DELTA1,DL1,Delta,NEDBAS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 28514
MIM: 606582
HGNC: 2908
Ensembl: ENSG00000198719
Variants:
dbSNP: 28514
ClinVar: 28514
TCGA: ENSG00000198719
COSMIC: DLL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198719 | ENST00000366756 | O00548 |
| ENSG00000198719 | ENST00000366756 | A0A384P5C6 |
| ENSG00000198719 | ENST00000630500 | A0A0D9SF76 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35750470 | 2023 | Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma. | 8 |
| 36935482 | 2023 | The phenotypic spectrum of terminal 6q deletions based on a large cohort derived from social media and literature: a prominent role for DLL1. | 1 |
| 35750470 | 2023 | Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in oesophageal adenocarcinoma. | 8 |
| 36935482 | 2023 | The phenotypic spectrum of terminal 6q deletions based on a large cohort derived from social media and literature: a prominent role for DLL1. | 1 |
| 34375432 | 2022 | Association Between Soluble Notch Ligand Delta-like Ligand 1 and Bleeding Complications in Patients With Dengue Fever Infection. | 1 |
| 34894355 | 2022 | Terminal 6q deletions cause brain malformations, a phenotype mimicking heterozygous DLL1 pathogenic variants: A multicenter retrospective case series. | 3 |
| 34375432 | 2022 | Association Between Soluble Notch Ligand Delta-like Ligand 1 and Bleeding Complications in Patients With Dengue Fever Infection. | 1 |
| 34894355 | 2022 | Terminal 6q deletions cause brain malformations, a phenotype mimicking heterozygous DLL1 pathogenic variants: A multicenter retrospective case series. | 3 |
| 33157082 | 2021 | Association of DLL1 with type 1 diabetes in patients characterized by low polygenic risk score. | 5 |
| 33157082 | 2021 | Association of DLL1 with type 1 diabetes in patients characterized by low polygenic risk score. | 5 |
| 32019397 | 2020 | The potential mechanism of miR-130b on promotion of the invasion and metastasis of hepatocellular carcinoma by inhibiting Notch-Dll1. | 5 |
| 32132030 | 2020 | Silencing Delta-like 1 Expression Induces Migratory Features in Pancreatic Cancer Cells Through Stimulation of Src and p38 Signalling Pathway. | 0 |
| 32019397 | 2020 | The potential mechanism of miR-130b on promotion of the invasion and metastasis of hepatocellular carcinoma by inhibiting Notch-Dll1. | 5 |
| 32132030 | 2020 | Silencing Delta-like 1 Expression Induces Migratory Features in Pancreatic Cancer Cells Through Stimulation of Src and p38 Signalling Pathway. | 0 |
| 29678681 | 2019 | Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. | 5 |
Citation
Dessen P
DLL1 (delta like canonical Notch ligand 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45960/dll1
