| Nomenclature |
|---|
| HGNC (Hugo) | DLX3 2916 |
| Cards |
|---|
| Entrez_Gene (NCBI) | DLX3 1747 distal-less homeobox 3 |
| Aliases | AI4; TDO |
| GeneCards (Weizmann) | DLX3 |
| Ensembl hg19 (Hinxton) | ENSG00000064195 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000064195 [Gene_View] ENSG00000064195 [Sequence] chr17:49990005-49995224 [Contig_View] DLX3 [Vega] |
| ICGC DataPortal | ENSG00000064195 |
| TCGA cBioPortal | DLX3 |
| AceView (NCBI) | DLX3 |
| Genatlas (Paris) | DLX3 |
| WikiGenes | 1747 |
| SOURCE (Princeton) | DLX3 |
| Genetics Home Reference (NIH) | DLX3 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | DLX3 - chr17:49990005-49995224 - 17q21.33 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | DLX3 - 17q21.33 [Description] (hg19-Feb_2009) |
| GoldenPath | DLX3 - 17q21.33 [CytoView hg19] DLX3 - 17q21.33 [CytoView hg38] |
| ImmunoBase | ENSG00000064195 |
| Mapping of homologs : NCBI | DLX3 [Mapview hg19] DLX3 [Mapview hg38] |
| OMIM | 104510 190320 600525 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA604314 AK075167 AK313257 BC012361 BC028970 |
| RefSeq transcript (Entrez) | NM_005220 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | DLX3 |
| Cluster EST : Unigene | Hs.134194 [ NCBI ] |
| CGAP (NCI) | Hs.134194 |
| Alternative Splicing Gallery | ENSG00000064195 |
| Gene Expression | DLX3 [ NCBI-GEO ] DLX3 [ EBI - ARRAY_EXPRESS ]
DLX3 [ SEEK ] DLX3 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | DLX3 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1747 |
| GTEX Portal (Tissue expression) | DLX3 |
| Human Protein Atlas | ENSG00000064195-DLX3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O60479 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O60479 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O60479 |
| Splice isoforms : SwissVar | O60479 |
| PhosPhoSitePlus | O60479 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Distal-less_N Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa HTH_motif |
| Domain families : Pfam (Sanger) | DLL_N (PF12413) Homeobox (PF00046) |
| Domain families : Pfam (NCBI) | pfam12413 pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | DLX3 |
| DMDM Disease mutations | 1747 |
| Blocks (Seattle) | DLX3 |
| PDB (RSDB) | 4XRS |
| PDB Europe | 4XRS |
| PDB (PDBSum) | 4XRS |
| PDB (IMB) | 4XRS |
| Structural Biology KnowledgeBase | 4XRS |
| SCOP (Structural Classification of Proteins) | 4XRS |
| CATH (Classification of proteins structures) | 4XRS |
| Superfamily | O60479 |
| Human Protein Atlas [tissue] | ENSG00000064195-DLX3 [tissue] |
| Peptide Atlas | O60479 |
| HPRD | 02752 |
| IPI | IPI00029716 IPI01021511 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O60479 |
| IntAct (EBI) | O60479 |
| FunCoup | ENSG00000064195 |
| BioGRID | DLX3 |
| STRING (EMBL) | DLX3 |
| ZODIAC | DLX3 |
| Ontologies - Pathways |
|---|
| QuickGO | O60479 |
| Ontology : AmiGO | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development placenta development DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus regulation of transcription by RNA polymerase II cell differentiation epithelial cell differentiation odontogenesis of dentin-containing tooth sequence-specific DNA binding positive regulation of transcription by RNA polymerase II odontoblast differentiation |
| Ontology : EGO-EBI | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development placenta development DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus regulation of transcription by RNA polymerase II cell differentiation epithelial cell differentiation odontogenesis of dentin-containing tooth sequence-specific DNA binding positive regulation of transcription by RNA polymerase II odontoblast differentiation |
| NDEx Network | DLX3 |
| Atlas of Cancer Signalling Network | DLX3 |
| Wikipedia pathways | DLX3 |
| Orthology - Evolution |
|---|
| OrthoDB | 1747 |
| GeneTree (enSembl) | ENSG00000064195 |
| Phylogenetic Trees/Animal Genes : TreeFam | DLX3 |
| HOGENOM | O60479 |
| Homologs : HomoloGene | DLX3 |
| Homology/Alignments : Family Browser (UCSC) | DLX3 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | DLX3 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | DLX3 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | DLX3 |
| dbVar | DLX3 |
| ClinVar | DLX3 |
| 1000_Genomes | DLX3 |
| Exome Variant Server | DLX3 |
| ExAC (Exome Aggregation Consortium) | ENSG00000064195 |
| GNOMAD Browser | ENSG00000064195 |
| Varsome Browser | DLX3 |
| Genetic variants : HAPMAP | 1747 |
| Genomic Variants (DGV) | DLX3 [DGVbeta] |
| DECIPHER | DLX3 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | DLX3 |
| Mutations |
|---|
| ICGC Data Portal | DLX3 |
| TCGA Data Portal | DLX3 |
| Broad Tumor Portal | DLX3 |
| OASIS Portal | DLX3 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | DLX3 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | DLX3 |
| Mutations and Diseases : HGMD | DLX3 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search DLX3 |
| DgiDB (Drug Gene Interaction Database) | DLX3 |
| DoCM (Curated mutations) | DLX3 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | DLX3 (select a term) |
| intoGen | DLX3 |
| Cancer3D | DLX3(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 104510 190320 600525 |
| Orphanet | 2971 14607 |
| DisGeNET | DLX3 |
| Medgen | DLX3 |
| Genetic Testing Registry | DLX3
|
| NextProt | O60479 [Medical] |
| TSGene | 1747 |
| GENETests | DLX3 |
| Target Validation | DLX3 |
| Huge Navigator |
DLX3 [HugePedia] |
| snp3D : Map Gene to Disease | 1747 |
| BioCentury BCIQ | DLX3 |
| ClinGen | DLX3 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1747 |
| Chemical/Pharm GKB Gene | PA27371 |
| Clinical trial | DLX3 |
| Miscellaneous |
|---|
| canSAR (ICR) | DLX3 (select the gene name) |
| DataMed Index | DLX3 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 58 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | DLX3 |
| EVEX | DLX3 |
| GoPubMed | DLX3 |
| iHOP | DLX3 |
