| Nomenclature |
HGNC (Hugo) | DLX3 2916 |
| Cards |
Entrez_Gene (NCBI) | DLX3 1747 distal-less homeobox 3 |
Aliases | AI4; TDO |
GeneCards (Weizmann) | DLX3 |
Ensembl hg19 (Hinxton) | ENSG00000064195 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000064195 [Gene_View]  ENSG00000064195 [Sequence] chr17:49990005-49995224 [Contig_View] DLX3 [Vega] |
ICGC DataPortal | ENSG00000064195 |
TCGA cBioPortal | DLX3 |
AceView (NCBI) | DLX3 |
Genatlas (Paris) | DLX3 |
WikiGenes | 1747 |
SOURCE (Princeton) | DLX3 |
Genetics Home Reference (NIH) | DLX3 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | DLX3 - chr17:49990005-49995224 - 17q21.33 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | DLX3 - 17q21.33 [Description] (hg19-Feb_2009) |
GoldenPath | DLX3 - 17q21.33 [CytoView hg19] DLX3 - 17q21.33 [CytoView hg38] |
ImmunoBase | ENSG00000064195 |
Mapping of homologs : NCBI | DLX3 [Mapview hg19] DLX3 [Mapview hg38] |
OMIM | 104510 190320 600525 |
| Gene and transcription |
Genbank (Entrez) | AA604314 AK075167 AK313257 BC012361 BC028970 |
RefSeq transcript (Entrez) | NM_005220 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | DLX3 |
Cluster EST : Unigene | Hs.134194 [ NCBI ] |
CGAP (NCI) | Hs.134194 |
Alternative Splicing Gallery | ENSG00000064195 |
Gene Expression | DLX3 [ NCBI-GEO ] DLX3 [ EBI - ARRAY_EXPRESS ]
DLX3 [ SEEK ] DLX3 [ MEM ] |
Gene Expression Viewer (FireBrowse) | DLX3 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 1747 |
GTEX Portal (Tissue expression) | DLX3 |
Human Protein Atlas | ENSG00000064195-DLX3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | O60479 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | O60479 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | O60479 |
Splice isoforms : SwissVar | O60479 |
PhosPhoSitePlus | O60479 |
Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
Domains : Interpro (EBI) | Distal-less_N Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa HTH_motif |
Domain families : Pfam (Sanger) | DLL_N (PF12413) Homeobox (PF00046) |
Domain families : Pfam (NCBI) | pfam12413 pfam00046 |
Domain families : Smart (EMBL) | HOX (SM00389) |
Conserved Domain (NCBI) | DLX3 |
DMDM Disease mutations | 1747 |
Blocks (Seattle) | DLX3 |
PDB (RSDB) | 4XRS |
PDB Europe | 4XRS |
PDB (PDBSum) | 4XRS |
PDB (IMB) | 4XRS |
Structural Biology KnowledgeBase | 4XRS |
SCOP (Structural Classification of Proteins) | 4XRS |
CATH (Classification of proteins structures) | 4XRS |
Superfamily | O60479 |
Human Protein Atlas [tissue] | ENSG00000064195-DLX3 [tissue] |
Peptide Atlas | O60479 |
HPRD | 02752 |
IPI | IPI00029716 IPI01021511 |
| Protein Interaction databases |
DIP (DOE-UCLA) | O60479 |
IntAct (EBI) | O60479 |
FunCoup | ENSG00000064195 |
BioGRID | DLX3 |
STRING (EMBL) | DLX3 |
ZODIAC | DLX3 |
| Ontologies - Pathways |
QuickGO | O60479 |
Ontology : AmiGO | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development placenta development DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus regulation of transcription by RNA polymerase II cell differentiation epithelial cell differentiation odontogenesis of dentin-containing tooth sequence-specific DNA binding positive regulation of transcription by RNA polymerase II odontoblast differentiation |
Ontology : EGO-EBI | RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development placenta development DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus regulation of transcription by RNA polymerase II cell differentiation epithelial cell differentiation odontogenesis of dentin-containing tooth sequence-specific DNA binding positive regulation of transcription by RNA polymerase II odontoblast differentiation |
NDEx Network | DLX3 |
Atlas of Cancer Signalling Network | DLX3 |
Wikipedia pathways | DLX3 |
| Orthology - Evolution |
OrthoDB | 1747 |
GeneTree (enSembl) | ENSG00000064195 |
Phylogenetic Trees/Animal Genes : TreeFam | DLX3 |
HOGENOM | O60479 |
Homologs : HomoloGene | DLX3 |
Homology/Alignments : Family Browser (UCSC) | DLX3 |
| Gene fusions - Rearrangements |
Fusion : Quiver | DLX3 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | DLX3 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | DLX3 |
dbVar | DLX3 |
ClinVar | DLX3 |
1000_Genomes | DLX3 |
Exome Variant Server | DLX3 |
ExAC (Exome Aggregation Consortium) | ENSG00000064195 |
GNOMAD Browser | ENSG00000064195 |
Varsome Browser | DLX3 |
Genetic variants : HAPMAP | 1747 |
Genomic Variants (DGV) | DLX3 [DGVbeta] |
DECIPHER | DLX3 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | DLX3 |
| Mutations |
ICGC Data Portal | DLX3 |
TCGA Data Portal | DLX3 |
Broad Tumor Portal | DLX3 |
OASIS Portal | DLX3 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | DLX3 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | DLX3 |
Mutations and Diseases : HGMD | DLX3 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search DLX3 |
DgiDB (Drug Gene Interaction Database) | DLX3 |
DoCM (Curated mutations) | DLX3 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | DLX3 (select a term) |
intoGen | DLX3 |
Cancer3D | DLX3(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 104510 190320 600525 |
Orphanet | 2971 14607 |
DisGeNET | DLX3 |
Medgen | DLX3 |
Genetic Testing Registry | DLX3
|
NextProt | O60479 [Medical] |
TSGene | 1747 |
GENETests | DLX3 |
Target Validation | DLX3 |
Huge Navigator |
DLX3 [HugePedia] |
snp3D : Map Gene to Disease | 1747 |
BioCentury BCIQ | DLX3 |
ClinGen | DLX3 |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 1747 |
Chemical/Pharm GKB Gene | PA27371 |
Clinical trial | DLX3 |
| Miscellaneous |
---|
canSAR (ICR) | DLX3 (select the gene name) |
DataMed Index | DLX3 |
| Probes |
---|
| Litterature |
---|
PubMed | 58 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | DLX3 |
EVEX | DLX3 |
GoPubMed | DLX3 |
iHOP | DLX3 |