Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1761
MIM: 602424
HGNC: 2934
Ensembl: ENSG00000137090
Variants:
dbSNP: 1761
ClinVar: 1761
TCGA: ENSG00000137090
COSMIC: DMRT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137090 | ENST00000382276 | Q9Y5R6 |
| ENSG00000137090 | ENST00000569227 | H3BN61 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36572623 | 2023 | Functional assessment of DMRT1 variants and their pathogenicity for isolated male infertility. | 0 |
| 37709822 | 2023 | DMRT1 regulates human germline commitment. | 6 |
| 36572623 | 2023 | Functional assessment of DMRT1 variants and their pathogenicity for isolated male infertility. | 0 |
| 37709822 | 2023 | DMRT1 regulates human germline commitment. | 6 |
| 30067948 | 2018 | Protein expression of the transcription factors DMRT1, TCLF5, and OCT4 in selected germ cell neoplasms of the testis. | 4 |
| 30272154 | 2018 | DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads. | 8 |
| 30067948 | 2018 | Protein expression of the transcription factors DMRT1, TCLF5, and OCT4 in selected germ cell neoplasms of the testis. | 4 |
| 30272154 | 2018 | DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads. | 8 |
| 26906082 | 2016 | Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages. | 9 |
| 26906082 | 2016 | Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages. | 9 |
| 26005864 | 2015 | An ancient protein-DNA interaction underlying metazoan sex determination. | 46 |
| 26139570 | 2015 | Rare double sex and mab-3-related transcription factor 1 regulatory variants in severe spermatogenic failure. | 7 |
| 26005864 | 2015 | An ancient protein-DNA interaction underlying metazoan sex determination. | 46 |
| 26139570 | 2015 | Rare double sex and mab-3-related transcription factor 1 regulatory variants in severe spermatogenic failure. | 7 |
| 24934491 | 2014 | DMRT1 mutations are rarely associated with male infertility. | 15 |
Citation
Dessen P
DMRT1 (doublesex and mab-3 related transcription factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/52809/dmrt1
