Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DNAI1 (dynein axonemal intermediate chain 1)

Identity

Alias_namesdynein, axonemal, intermediate polypeptide 1
Alias_symbol (synonym)DIC1
PCD
CILD1
Other aliasICS1
HGNC (Hugo) DNAI1
LocusID (NCBI) 27019
Atlas_Id 62557
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 34458752 and ends at 34520989 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAI1 (9p13.3) / MSH2 (2p21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DNAI1   2954
Cards
Entrez_Gene (NCBI)DNAI1  27019  dynein axonemal intermediate chain 1
AliasesCILD1; DIC1; ICS1; PCD
GeneCards (Weizmann)DNAI1
Ensembl hg19 (Hinxton)ENSG00000122735 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122735 [Gene_View]  ENSG00000122735 [Sequence]  chr9:34458752-34520989 [Contig_View]  DNAI1 [Vega]
ICGC DataPortalENSG00000122735
TCGA cBioPortalDNAI1
AceView (NCBI)DNAI1
Genatlas (Paris)DNAI1
WikiGenes27019
SOURCE (Princeton)DNAI1
Genetics Home Reference (NIH)DNAI1
Genomic and cartography
GoldenPath hg38 (UCSC)DNAI1  -     chr9:34458752-34520989 +  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAI1  -     9p13.3   [Description]    (hg19-Feb_2009)
GoldenPathDNAI1 - 9p13.3 [CytoView hg19]  DNAI1 - 9p13.3 [CytoView hg38]
ImmunoBaseENSG00000122735
Mapping of homologs : NCBIDNAI1 [Mapview hg19]  DNAI1 [Mapview hg38]
OMIM244400   604366   
Gene and transcription
Genbank (Entrez)AF091619 AI784188 AK057687 AK290696 AK302186
RefSeq transcript (Entrez)NM_001281428 NM_012144
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAI1
Cluster EST : UnigeneHs.112667 [ NCBI ]
CGAP (NCI)Hs.112667
Alternative Splicing GalleryENSG00000122735
Gene ExpressionDNAI1 [ NCBI-GEO ]   DNAI1 [ EBI - ARRAY_EXPRESS ]   DNAI1 [ SEEK ]   DNAI1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAI1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27019
GTEX Portal (Tissue expression)DNAI1
Human Protein AtlasENSG00000122735-DNAI1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UI46   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UI46  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UI46
Splice isoforms : SwissVarQ9UI46
PhosPhoSitePlusQ9UI46
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)DNAI1
DMDM Disease mutations27019
Blocks (Seattle)DNAI1
SuperfamilyQ9UI46
Human Protein Atlas [tissue]ENSG00000122735-DNAI1 [tissue]
Peptide AtlasQ9UI46
HPRD05080
IPIIPI00006030   IPI00909607   IPI00922640   IPI00514431   IPI00976227   IPI00646213   IPI00981774   
Protein Interaction databases
DIP (DOE-UCLA)Q9UI46
IntAct (EBI)Q9UI46
FunCoupENSG00000122735
BioGRIDDNAI1
STRING (EMBL)DNAI1
ZODIACDNAI1
Ontologies - Pathways
QuickGOQ9UI46
Ontology : AmiGOcilium movement  cilium movement  motor activity  protein binding  cytoskeleton  microtubule  cilium  microtubule-based movement  determination of left/right symmetry  ATP-dependent microtubule motor activity, plus-end-directed  flagellated sperm motility  outer dynein arm  outer dynein arm  outer dynein arm assembly  outer dynein arm assembly  dynein light chain binding  dynein heavy chain binding  
Ontology : EGO-EBIcilium movement  cilium movement  motor activity  protein binding  cytoskeleton  microtubule  cilium  microtubule-based movement  determination of left/right symmetry  ATP-dependent microtubule motor activity, plus-end-directed  flagellated sperm motility  outer dynein arm  outer dynein arm  outer dynein arm assembly  outer dynein arm assembly  dynein light chain binding  dynein heavy chain binding  
NDEx NetworkDNAI1
Atlas of Cancer Signalling NetworkDNAI1
Wikipedia pathwaysDNAI1
Orthology - Evolution
OrthoDB27019
GeneTree (enSembl)ENSG00000122735
Phylogenetic Trees/Animal Genes : TreeFamDNAI1
HOGENOMQ9UI46
Homologs : HomoloGeneDNAI1
Homology/Alignments : Family Browser (UCSC)DNAI1
Gene fusions - Rearrangements
Fusion : QuiverDNAI1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAI1
dbVarDNAI1
ClinVarDNAI1
1000_GenomesDNAI1 
Exome Variant ServerDNAI1
ExAC (Exome Aggregation Consortium)ENSG00000122735
GNOMAD BrowserENSG00000122735
Varsome BrowserDNAI1
Genetic variants : HAPMAP27019
Genomic Variants (DGV)DNAI1 [DGVbeta]
DECIPHERDNAI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAI1 
Mutations
ICGC Data PortalDNAI1 
TCGA Data PortalDNAI1 
Broad Tumor PortalDNAI1
OASIS PortalDNAI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAI1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNAI1
Mutations and Diseases : HGMDDNAI1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Primary Ciliary Dyskinesia variant database
BioMutasearch DNAI1
DgiDB (Drug Gene Interaction Database)DNAI1
DoCM (Curated mutations)DNAI1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAI1 (select a term)
intoGenDNAI1
Cancer3DDNAI1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM244400    604366   
Orphanet665   
DisGeNETDNAI1
MedgenDNAI1
Genetic Testing Registry DNAI1
NextProtQ9UI46 [Medical]
TSGene27019
GENETestsDNAI1
Target ValidationDNAI1
Huge Navigator DNAI1 [HugePedia]
snp3D : Map Gene to Disease27019
BioCentury BCIQDNAI1
ClinGenDNAI1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27019
Chemical/Pharm GKB GenePA27407
Clinical trialDNAI1
Miscellaneous
canSAR (ICR)DNAI1 (select the gene name)
DataMed IndexDNAI1
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAI1
EVEXDNAI1
GoPubMedDNAI1
iHOPDNAI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Sep 3 15:25:58 CEST 2019
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