Identity
HGNC
LOCATION
2q35
LOCUSID
ALIAS
CMT2T,DSMA5,HSJ-1,HSJ1,HSPF3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3300
MIM: 604139
HGNC: 5228
Ensembl: ENSG00000135924
Variants:
dbSNP: 3300
ClinVar: 3300
TCGA: ENSG00000135924
COSMIC: DNAJB2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36746103 | 2023 | The heat shock protein DNAJB2 as a novel biomarker for essential thrombocythemia diagnosis associated with immune infiltration. | 2 |
| 36746103 | 2023 | The heat shock protein DNAJB2 as a novel biomarker for essential thrombocythemia diagnosis associated with immune infiltration. | 2 |
| 35286755 | 2022 | DNAJB2-related Charcot-Marie-Tooth disease type 2: Pathomechanism insights and phenotypic spectrum widening. | 4 |
| 35286755 | 2022 | DNAJB2-related Charcot-Marie-Tooth disease type 2: Pathomechanism insights and phenotypic spectrum widening. | 4 |
| 31682009 | 2020 | Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes. | 2 |
| 31682009 | 2020 | Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes. | 2 |
| 28031292 | 2017 | Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain. | 7 |
| 28031292 | 2017 | Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain. | 7 |
| 27449489 | 2016 | Identification of a Large DNAJB2 Deletion in a Family with Spinal Muscular Atrophy and Parkinsonism. | 27 |
| 27449489 | 2016 | Identification of a Large DNAJB2 Deletion in a Family with Spinal Muscular Atrophy and Parkinsonism. | 27 |
| 25274842 | 2014 | HSJ1-related hereditary neuropathies: novel mutations and extended clinical spectrum. | 22 |
| 25274842 | 2014 | HSJ1-related hereditary neuropathies: novel mutations and extended clinical spectrum. | 22 |
| 24023695 | 2013 | Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. | 26 |
| 24023695 | 2013 | Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. | 26 |
| 22522442 | 2012 | A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation. | 35 |
Citation
Dessen P
DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46852/dnajb2
