DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8)

2007-04-01  

Identity

HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
CT156,DJ6

Other Information

Locus ID:

NCBI: 165721
MIM: 611337
HGNC: 23699
Ensembl: ENSG00000179407

Variants:

dbSNP: 165721
ClinVar: 165721
TCGA: ENSG00000179407
COSMIC: DNAJB8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179407ENST00000319153Q8NHS0
ENSG00000179407ENST00000319153A0A140VJI2
ENSG00000179407ENST00000469083Q8NHS0
ENSG00000179407ENST00000469083A0A140VJI2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

References

Pubmed IDYearTitleCitations
201595552010A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.109
225522852012HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.40
236129752013The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.37
244505412014Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.21
277135072016Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.8
293160772018Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.2

Citation

Dessen P

DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47309/dnajb8