DNAJC15 (DnaJ heat shock protein family (Hsp40) member C15)

2007-02-01  

Identity

HGNC
LOCATION
13q14.11
LOCUSID
ALIAS
DNAJD1,HSD18,MCJ
FUSION GENES

Other Information

Locus ID:

NCBI: 29103
MIM: 615339
HGNC: 20325
Ensembl: ENSG00000120675

Variants:

dbSNP: 29103
ClinVar: 29103
TCGA: ENSG00000120675
COSMIC: DNAJC15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120675ENST00000379221Q9Y5T4

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
147295892004Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.29
160499742006Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours.21
172830402007Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression.18
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
232638642013Methylation-controlled J-protein MCJ acts in the import of proteins into human mitochondria.17
272340562016Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.16
292339772017The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.12
246033292014Chaperoning mitochondrial permeability transition: regulation of transition pore complex by a J-protein, DnaJC15.7
264198082015Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages.7
183246242008Transient ectopic expression as a method to detect genes conferring drug resistance.5

Citation

Dessen P

DNAJC15 (DnaJ heat shock protein family (Hsp40) member C15)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43753/dnajc15