Identity
HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
p56DOK,p56dok-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9046
MIM: 604997
HGNC: 2991
Ensembl: ENSG00000147443
Variants:
dbSNP: 9046
ClinVar: 9046
TCGA: ENSG00000147443
COSMIC: DOK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000147443 | ENST00000276420 | O60496 |
| ENSG00000147443 | ENST00000517422 | G3V114 |
| ENSG00000147443 | ENST00000518197 | E5RIG9 |
| ENSG00000147443 | ENST00000523932 | E5RJ11 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34505522 | 2021 | Introduction to DOK2 and its potential role in cancer. | 7 |
| 34505522 | 2021 | Introduction to DOK2 and its potential role in cancer. | 7 |
| 27975172 | 2018 | Region-Specific Dok2 Overexpression Associates with Poor Prognosis in Human Astrocytoma. | 4 |
| 29150948 | 2018 | Methylation-associated DOK1 and DOK2 down-regulation: Potential biomarkers for predicting adverse prognosis in acute myeloid leukemia. | 7 |
| 27975172 | 2018 | Region-Specific Dok2 Overexpression Associates with Poor Prognosis in Human Astrocytoma. | 4 |
| 29150948 | 2018 | Methylation-associated DOK1 and DOK2 down-regulation: Potential biomarkers for predicting adverse prognosis in acute myeloid leukemia. | 7 |
| 28841444 | 2017 | Herpes simplex virus 1 infection of T cells causes VP11/12-dependent phosphorylation and degradation of the cellular protein Dok-2. | 6 |
| 28841444 | 2017 | Herpes simplex virus 1 infection of T cells causes VP11/12-dependent phosphorylation and degradation of the cellular protein Dok-2. | 6 |
| 27265473 | 2016 | Expression of DOK1, 2, and 3 genes in HTLV-1-infected T cells. | 3 |
| 27265473 | 2016 | Expression of DOK1, 2, and 3 genes in HTLV-1-infected T cells. | 3 |
| 25252871 | 2015 | Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML). | 6 |
| 25252871 | 2015 | Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML). | 6 |
| 24963146 | 2014 | Dok1 and Dok2 proteins regulate natural killer cell development and function. | 17 |
| 24963146 | 2014 | Dok1 and Dok2 proteins regulate natural killer cell development and function. | 17 |
| 24255704 | 2013 | DOK2 inhibits EGFR-mutated lung adenocarcinoma. | 9 |
Citation
Dessen P
DOK2 (docking protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40357/dok2
