Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DPF3 (double PHD fingers 3)

Identity

Alias_namesD4, zinc and double PHD fingers, family 3
Alias_symbol (synonym)cer-d4
Cerd4
FLJ14079
BAF45c
Other aliasBAF45C
CERD4
HGNC (Hugo) DPF3
LocusID (NCBI) 8110
Atlas_Id 54263
Location 14q24.2  [Link to chromosome band 14q24]
Location_base_pair Starts at 72661050 and ends at 72894101 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTA1 (14q32.33) / DPF3 (14q24.2)SASH1 (6q24.3) / DPF3 (14q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(6;14)(q24;q24) SASH1/DPF3

External links

Nomenclature
HGNC (Hugo)DPF3   17427
Cards
Entrez_Gene (NCBI)DPF3  8110  double PHD fingers 3
AliasesBAF45C; CERD4
GeneCards (Weizmann)DPF3
Ensembl hg19 (Hinxton)ENSG00000205683 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205683 [Gene_View]  ENSG00000205683 [Sequence]  chr14:72661050-72894101 [Contig_View]  DPF3 [Vega]
ICGC DataPortalENSG00000205683
TCGA cBioPortalDPF3
AceView (NCBI)DPF3
Genatlas (Paris)DPF3
WikiGenes8110
SOURCE (Princeton)DPF3
Genetics Home Reference (NIH)DPF3
Genomic and cartography
GoldenPath hg38 (UCSC)DPF3  -     chr14:72661050-72894101 -  14q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPF3  -     14q24.2   [Description]    (hg19-Feb_2009)
GoldenPathDPF3 - 14q24.2 [CytoView hg19]  DPF3 - 14q24.2 [CytoView hg38]
Genome Data Viewer NCBIDPF3 [Mapview hg19]  
OMIM601672   
Gene and transcription
Genbank (Entrez)AK024141 AK123045 AK124615 AK124946 AK126074
RefSeq transcript (Entrez)NM_001280542 NM_001280543 NM_001280544 NM_012074
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPF3
Alternative Splicing GalleryENSG00000205683
Gene ExpressionDPF3 [ NCBI-GEO ]   DPF3 [ EBI - ARRAY_EXPRESS ]   DPF3 [ SEEK ]   DPF3 [ MEM ]
Gene Expression Viewer (FireBrowse)DPF3 [ Firebrowse - Broad ]
GenevisibleExpression of DPF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8110
GTEX Portal (Tissue expression)DPF3
Human Protein AtlasENSG00000205683-DPF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92784   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92784  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92784
Splice isoforms : SwissVarQ92784
PhosPhoSitePlusQ92784
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)DPF3    Requiem/DPF_N_dom    Znf_C2H2_sf    Znf_C2H2_type    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PHD (PF00628)    Requiem_N (PF14051)   
Domain families : Pfam (NCBI)pfam00628    pfam14051   
Domain families : Smart (EMBL)PHD (SM00249)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)DPF3
DMDM Disease mutations8110
PDB (RSDB)2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
PDB Europe2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
PDB (PDBSum)2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
PDB (IMB)2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
Structural Biology KnowledgeBase2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
SCOP (Structural Classification of Proteins)2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
CATH (Classification of proteins structures)2KWJ    2KWK    2KWN    2KWO    5I3L    5SZB    5SZC   
SuperfamilyQ92784
Human Protein Atlas [tissue]ENSG00000205683-DPF3 [tissue]
Peptide AtlasQ92784
HPRD03395
IPIIPI00425378   IPI01012933   IPI00915028   IPI00915029   IPI00914968   IPI01025865   IPI01024717   IPI00976132   
Protein Interaction databases
DIP (DOE-UCLA)Q92784
IntAct (EBI)Q92784
FunCoupENSG00000205683
BioGRIDDPF3
STRING (EMBL)DPF3
ZODIACDPF3
Ontologies - Pathways
QuickGOQ92784
Ontology : AmiGOhistone acetyltransferase complex  nuclear chromatin  nucleic acid binding  histone acetyltransferase activity  nucleus  nucleoplasm  nervous system development  biological_process  zinc ion binding  histone acetylation  histone binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  nBAF complex  nBAF complex  
Ontology : EGO-EBIhistone acetyltransferase complex  nuclear chromatin  nucleic acid binding  histone acetyltransferase activity  nucleus  nucleoplasm  nervous system development  biological_process  zinc ion binding  histone acetylation  histone binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  nBAF complex  nBAF complex  
NDEx NetworkDPF3
Atlas of Cancer Signalling NetworkDPF3
Wikipedia pathwaysDPF3
Orthology - Evolution
OrthoDB8110
GeneTree (enSembl)ENSG00000205683
Phylogenetic Trees/Animal Genes : TreeFamDPF3
HOGENOMQ92784
Homologs : HomoloGeneDPF3
Homology/Alignments : Family Browser (UCSC)DPF3
Gene fusions - Rearrangements
Fusion : MitelmanSASH1/DPF3 [6q24.3/14q24.2]  
Fusion : QuiverDPF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPF3
dbVarDPF3
ClinVarDPF3
1000_GenomesDPF3 
Exome Variant ServerDPF3
GNOMAD BrowserENSG00000205683
Varsome BrowserDPF3
Genetic variants : HAPMAP8110
Genomic Variants (DGV)DPF3 [DGVbeta]
DECIPHERDPF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPF3 
Mutations
ICGC Data PortalDPF3 
TCGA Data PortalDPF3 
Broad Tumor PortalDPF3
OASIS PortalDPF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDPF3
Mutations and Diseases : HGMDDPF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect DPF3
DgiDB (Drug Gene Interaction Database)DPF3
DoCM (Curated mutations)DPF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPF3 (select a term)
intoGenDPF3
Cancer3DDPF3 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601672   
Orphanet
DisGeNETDPF3
MedgenDPF3
Genetic Testing Registry DPF3
NextProtQ92784 [Medical]
TSGene8110
GENETestsDPF3
Open Targets GeneticsENSG00000205683  [validation]
snp3D : Map Gene to Disease8110
BioCentury BCIQDPF3
ClinGenDPF3
Clinical trials, drugs, therapy
Protein Interactions : CTD8110
Pharm GKB GenePA134888535
Clinical trialDPF3
Miscellaneous
canSAR (ICR)DPF3 (select the gene name)
HarmonizomeDPF3
DataMed IndexDPF3
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPF3
EVEXDPF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 19:46:46 CEST 2020
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