Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DPH1 (diphthamide biosynthesis 1)

Identity

Alias_namesDPH2L
DPH2L1
diptheria toxin resistance protein required for diphthamide biosynthesis-like 1 (S. cerevisiae)
DPH-like 1 (S. cerevisiae)
DPH1 homolog (S. cerevisiae)
Alias_symbol (synonym)OVCA1
Other aliasDEDSSH
HGNC (Hugo) DPH1
LocusID (NCBI) 1801
Atlas_Id 40359
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 2030112 and ends at 2043431 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DPH1 (17p13.3) / CSNK1D (17q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DPH1   3003
Cards
Entrez_Gene (NCBI)DPH1  1801  diphthamide biosynthesis 1
AliasesDEDSSH; DPH2L; DPH2L1; OVCA1
GeneCards (Weizmann)DPH1
Ensembl hg19 (Hinxton)ENSG00000108963 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108963 [Gene_View]  ENSG00000108963 [Sequence]  chr17:2030112-2043431 [Contig_View]  DPH1 [Vega]
ICGC DataPortalENSG00000108963
TCGA cBioPortalDPH1
AceView (NCBI)DPH1
Genatlas (Paris)DPH1
WikiGenes1801
SOURCE (Princeton)DPH1
Genetics Home Reference (NIH)DPH1
Genomic and cartography
GoldenPath hg38 (UCSC)DPH1  -     chr17:2030112-2043431 +  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPH1  -     17p13.3   [Description]    (hg19-Feb_2009)
GoldenPathDPH1 - 17p13.3 [CytoView hg19]  DPH1 - 17p13.3 [CytoView hg38]
ImmunoBaseENSG00000108963
Mapping of homologs : NCBIDPH1 [Mapview hg19]  DPH1 [Mapview hg38]
OMIM603527   616901   
Gene and transcription
Genbank (Entrez)AF321876 AK090530 AK098268 AK297947 AK314015
RefSeq transcript (Entrez)NM_001346574 NM_001346575 NM_001346576 NM_001383
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPH1
Cluster EST : UnigeneHs.513856 [ NCBI ]
CGAP (NCI)Hs.513856
Alternative Splicing GalleryENSG00000108963
Gene ExpressionDPH1 [ NCBI-GEO ]   DPH1 [ EBI - ARRAY_EXPRESS ]   DPH1 [ SEEK ]   DPH1 [ MEM ]
Gene Expression Viewer (FireBrowse)DPH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1801
GTEX Portal (Tissue expression)DPH1
Human Protein AtlasENSG00000108963-DPH1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZG8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZG8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZG8
Splice isoforms : SwissVarQ9BZG8
PhosPhoSitePlusQ9BZG8
Domains : Interpro (EBI)DPH1/DPH2    DPH1/DPH2_euk_archaea   
Domain families : Pfam (Sanger)Diphthamide_syn (PF01866)   
Domain families : Pfam (NCBI)pfam01866   
Conserved Domain (NCBI)DPH1
DMDM Disease mutations1801
Blocks (Seattle)DPH1
SuperfamilyQ9BZG8
Human Protein Atlas [tissue]ENSG00000108963-DPH1 [tissue]
Peptide AtlasQ9BZG8
HPRD04634
IPIIPI00718991   IPI00868806   IPI00868847   IPI00908772   IPI00929734   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZG8
IntAct (EBI)Q9BZG8
FunCoupENSG00000108963
BioGRIDDPH1
STRING (EMBL)DPH1
ZODIACDPH1
Ontologies - Pathways
QuickGOQ9BZG8
Ontology : AmiGOprotein binding  nucleoplasm  cytosol  cell proliferation  transferase activity  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  cell junction  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytosol  cell proliferation  transferase activity  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  cell junction  
NDEx NetworkDPH1
Atlas of Cancer Signalling NetworkDPH1
Wikipedia pathwaysDPH1
Orthology - Evolution
OrthoDB1801
GeneTree (enSembl)ENSG00000108963
Phylogenetic Trees/Animal Genes : TreeFamDPH1
HOGENOMQ9BZG8
Homologs : HomoloGeneDPH1
Homology/Alignments : Family Browser (UCSC)DPH1
Gene fusions - Rearrangements
Fusion : QuiverDPH1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPH1
dbVarDPH1
ClinVarDPH1
1000_GenomesDPH1 
Exome Variant ServerDPH1
ExAC (Exome Aggregation Consortium)ENSG00000108963
GNOMAD BrowserENSG00000108963
Varsome BrowserDPH1
Genetic variants : HAPMAP1801
Genomic Variants (DGV)DPH1 [DGVbeta]
DECIPHERDPH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPH1 
Mutations
ICGC Data PortalDPH1 
TCGA Data PortalDPH1 
Broad Tumor PortalDPH1
OASIS PortalDPH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPH1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDPH1
Mutations and Diseases : HGMDDPH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPH1
DgiDB (Drug Gene Interaction Database)DPH1
DoCM (Curated mutations)DPH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPH1 (select a term)
intoGenDPH1
Cancer3DDPH1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603527    616901   
Orphanet23771   
DisGeNETDPH1
MedgenDPH1
Genetic Testing Registry DPH1
NextProtQ9BZG8 [Medical]
TSGene1801
GENETestsDPH1
Target ValidationDPH1
Huge Navigator DPH1 [HugePedia]
snp3D : Map Gene to Disease1801
BioCentury BCIQDPH1
ClinGenDPH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1801
Chemical/Pharm GKB GenePA27461
Clinical trialDPH1
Miscellaneous
canSAR (ICR)DPH1 (select the gene name)
DataMed IndexDPH1
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPH1
EVEXDPH1
GoPubMedDPH1
iHOPDPH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:40:56 CET 2019
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