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DPP3 (dipeptidyl peptidase 3)

Identity

Other namesDPPIII
HGNC (Hugo) DPP3
LocusID (NCBI) 10072
Atlas_Id 46396
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66247484 and ends at 66277130 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPP3 (11q13.2) / FKBP2 (11q13.1)DPP3 (11q13.2) / PACS1 (11q13.1)FAT3 (11q14.3) / DPP3 (11q13.2)
PPP6R3 (11q13.2) / DPP3 (11q13.2)DPP3 11q13.2 / FKBP2 11q13.1DPP3 11q13.2 / PACS1 11q13.1
FAT3 11q14.3 / DPP3 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPP3   3008
Cards
Entrez_Gene (NCBI)DPP3  10072  dipeptidyl peptidase 3
AliasesDPPIII
GeneCards (Weizmann)DPP3
Ensembl hg19 (Hinxton)ENSG00000254986 [Gene_View]  chr11:66247484-66277130 [Contig_View]  DPP3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000254986 [Gene_View]  chr11:66247484-66277130 [Contig_View]  DPP3 [Vega]
ICGC DataPortalENSG00000254986
TCGA cBioPortalDPP3
AceView (NCBI)DPP3
Genatlas (Paris)DPP3
WikiGenes10072
SOURCE (Princeton)DPP3
Genomic and cartography
GoldenPath hg19 (UCSC)DPP3  -     chr11:66247484-66277130 +  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DPP3  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblDPP3 - 11q13.2 [CytoView hg19]  DPP3 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIDPP3 [Mapview hg19]  DPP3 [Mapview hg38]
OMIM606818   
Gene and transcription
Genbank (Entrez)AB017970 AJ271216 AK021449 AK025984 AK222566
RefSeq transcript (Entrez)NM_001256670 NM_005700 NM_130443
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_032068 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)DPP3
Cluster EST : UnigeneHs.740670 [ NCBI ]
CGAP (NCI)Hs.740670
Alternative Splicing GalleryENSG00000254986
Gene ExpressionDPP3 [ NCBI-GEO ]   DPP3 [ EBI - ARRAY_EXPRESS ]   DPP3 [ SEEK ]   DPP3 [ MEM ]
Gene Expression Viewer (FireBrowse)DPP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10072
GTEX Portal (Tissue expression)DPP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NY33 (Uniprot)
NextProtQ9NY33  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NY33
Splice isoforms : SwissVarQ9NY33 (Swissvar)
Catalytic activity : Enzyme3.4.14.4 [ Enzyme-Expasy ]   3.4.14.43.4.14.4 [ IntEnz-EBI ]   3.4.14.4 [ BRENDA ]   3.4.14.4 [ KEGG ]   
PhosPhoSitePlusQ9NY33
Domains : Interpro (EBI)Dipeptidyl-peptase3   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations10072
Blocks (Seattle)DPP3
PDB (SRS)3FVY    3T6B    3T6J   
PDB (PDBSum)3FVY    3T6B    3T6J   
PDB (IMB)3FVY    3T6B    3T6J   
PDB (RSDB)3FVY    3T6B    3T6J   
Structural Biology KnowledgeBase3FVY    3T6B    3T6J   
SCOP (Structural Classification of Proteins)3FVY    3T6B    3T6J   
CATH (Classification of proteins structures)3FVY    3T6B    3T6J   
SuperfamilyQ9NY33
Human Protein AtlasENSG00000254986
Peptide AtlasQ9NY33
HPRD06012
IPIIPI00020672   IPI00645171   IPI00976265   IPI00976779   IPI00975587   IPI00978989   IPI00985505   IPI00979514   IPI01018750   
Protein Interaction databases
DIP (DOE-UCLA)Q9NY33
IntAct (EBI)Q9NY33
FunCoupENSG00000254986
BioGRIDDPP3
STRING (EMBL)DPP3
ZODIACDPP3
Ontologies - Pathways
QuickGOQ9NY33
Ontology : AmiGOprotein binding  nucleoplasm  cytoplasm  plasma membrane  proteolysis  metallopeptidase activity  dipeptidyl-peptidase activity  zinc ion binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytoplasm  plasma membrane  proteolysis  metallopeptidase activity  dipeptidyl-peptidase activity  zinc ion binding  extracellular exosome  
NDEx Network
Atlas of Cancer Signalling NetworkDPP3
Wikipedia pathwaysDPP3
Orthology - Evolution
OrthoDB10072
GeneTree (enSembl)ENSG00000254986
Phylogenetic Trees/Animal Genes : TreeFamDPP3
Homologs : HomoloGeneDPP3
Homology/Alignments : Family Browser (UCSC)DPP3
Gene fusions - Rearrangements
Fusion: TCGADPP3 11q13.2 FKBP2 11q13.1 LUAD
Fusion: TCGADPP3 11q13.2 PACS1 11q13.1 BRCA
Fusion: TCGAFAT3 11q14.3 DPP3 11q13.2 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerDPP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPP3
dbVarDPP3
ClinVarDPP3
1000_GenomesDPP3 
Exome Variant ServerDPP3
ExAC (Exome Aggregation Consortium)DPP3 (select the gene name)
Genetic variants : HAPMAP10072
Genomic Variants (DGV)DPP3 [DGVbeta]
Mutations
ICGC Data PortalDPP3 
TCGA Data PortalDPP3 
Broad Tumor PortalDPP3
OASIS PortalDPP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPP3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPP3
DgiDB (Drug Gene Interaction Database)DPP3
DoCM (Curated mutations)DPP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPP3 (select a term)
intoGenDPP3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:66247484-66277130  ENSG00000254986
CONAN: Copy Number AnalysisDPP3 
Mutations and Diseases : HGMDDPP3
OMIM606818   
MedgenDPP3
Genetic Testing Registry DPP3
NextProtQ9NY33 [Medical]
TSGene10072
GENETestsDPP3
Huge Navigator DPP3 [HugePedia]
snp3D : Map Gene to Disease10072
BioCentury BCIQDPP3
ClinGenDPP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10072
Chemical/Pharm GKB GenePA27466
Clinical trialDPP3
Miscellaneous
canSAR (ICR)DPP3 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPP3
EVEXDPP3
GoPubMedDPP3
iHOPDPP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:15:11 CEST 2016

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