DPP8 (dipeptidyl peptidase 8)

2011-02-01  

Identity

HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
DP8,DPRP-1,DPRP1,MST097,MSTP097,MSTP135,MSTP141
FUSION GENES

Other Information

Locus ID:

NCBI: 54878
MIM: 606819
HGNC: 16490
Ensembl: ENSG00000074603

Variants:

dbSNP: 54878
ClinVar: 54878
TCGA: ENSG00000074603
COSMIC: DPP8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000074603ENST00000300141Q6V1X1
ENSG00000074603ENST00000321147Q6V1X1
ENSG00000074603ENST00000341861Q6V1X1
ENSG00000074603ENST00000341861A0A024R5Z6
ENSG00000074603ENST00000358939Q6V1X1
ENSG00000074603ENST00000395652J3KPT0
ENSG00000074603ENST00000558529H0YKA2
ENSG00000074603ENST00000558559H0YK36
ENSG00000074603ENST00000558786H3BNM2
ENSG00000074603ENST00000559233Q6V1X1
ENSG00000074603ENST00000559233A0A024R5Z6
ENSG00000074603ENST00000559526H3BQ40
ENSG00000074603ENST00000560436H0YN53
ENSG00000074603ENST00000560665H0YMV1

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182758572008Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8.25
236087732013Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.22
235194732013Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism.18
195816302009The in vivo expression of dipeptidyl peptidases 8 and 9.16
167044182006Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.15
217110532011Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?12
237048212013Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.8
170409102006Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.6
205349822010Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.6
227361462012Expression profiling of dipeptidyl peptidase 8 and 9 in breast and ovarian carcinoma cell lines.6

Citation

Dessen P

DPP8 (dipeptidyl peptidase 8)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52087/dpp8