DPPA4 (developmental pluripotency associated 4)

2007-04-01  

Identity

HGNC
LOCATION
3q13.13
LOCUSID
ALIAS
2410091M23Rik
FUSION GENES

Other Information

Locus ID:

NCBI: 55211
MIM: 614125
HGNC: 19200
Ensembl: ENSG00000121570

Variants:

dbSNP: 55211
ClinVar: 55211
TCGA: ENSG00000121570
COSMIC: DPPA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121570ENST00000335658Q7L190
ENSG00000121570ENST00000477303C9J7A7
ENSG00000121570ENST00000495679F8WDC6

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of pluripotent stem cellsREACTOMER-HSA-452723
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferationREACTOMER-HSA-2892247

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360073772022Dynamic cytosolic foci of DPPA4 in human pluripotent stem cells.0
365818772022Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.2
360073772022Dynamic cytosolic foci of DPPA4 in human pluripotent stem cells.0
365818772022Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.2
333160322021Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.8
333160322021Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.8
311805272019High developmental pluripotency‑associated 4 expression promotes cell proliferation and glycolysis, and predicts poor prognosis in non‑small‑cell lung cancer.6
311805272019High developmental pluripotency‑associated 4 expression promotes cell proliferation and glycolysis, and predicts poor prognosis in non‑small‑cell lung cancer.6
293274672018ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.7
300319672018Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer.7
293274672018ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.7
300319672018Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer.7
266874792015The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.27
266874792015The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.27
239637362013Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.17

Citation

Dessen P

DPPA4 (developmental pluripotency associated 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47247/dppa4