Identity
HGNC
LOCATION
8p21.2
LOCUSID
ALIAS
CRMP-2,CRMP2,DHPRP2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1808
MIM: 602463
HGNC: 3014
Ensembl: ENSG00000092964
Variants:
dbSNP: 1808
ClinVar: 1808
TCGA: ENSG00000092964
COSMIC: DPYSL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000092964 | ENST00000311151 | Q16555 |
| ENSG00000092964 | ENST00000493789 | E5RFU4 |
| ENSG00000092964 | ENST00000521913 | A0A1C7CYX9 |
| ENSG00000092964 | ENST00000523027 | Q16555 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38583951 | 2024 | Zinc Deficiency Decreases Neurite Extension via CRMP2 Signal Pathway. | 0 |
| 38583951 | 2024 | Zinc Deficiency Decreases Neurite Extension via CRMP2 Signal Pathway. | 0 |
| 37174687 | 2023 | CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. | 1 |
| 37479784 | 2023 | DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders. | 6 |
| 37174687 | 2023 | CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease. | 1 |
| 37479784 | 2023 | DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders. | 6 |
| 34543692 | 2022 | Dysregulation of DPYSL2 expression by mTOR signaling in schizophrenia: Multi-level study of postmortem brain. | 6 |
| 34773219 | 2022 | Phosphorylation of CRMP2 by Cdk5 Negatively Regulates the Surface Delivery and Synaptic Function of AMPA Receptors. | 2 |
| 35203376 | 2022 | Characterization of Collapsin Response Mediator Protein 2 in Colorectal Cancer Progression in Subjects with Diabetic Comorbidity. | 2 |
| 35294884 | 2022 | A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer. | 3 |
| 35575798 | 2022 | DPYSL2 interacts with JAK1 to mediate breast cancer cell migration. | 6 |
| 35861646 | 2022 | De novo non-synonymous DPYSL2 (CRMP2) variants in two patients with intellectual disabilities and documentation of functional relevance through zebrafish rescue and cellular transfection experiments. | 3 |
| 35927239 | 2022 | CRMP2 derived from cancer associated fibroblasts facilitates progression of ovarian cancer via HIF-1α-glycolysis signaling pathway. | 9 |
| 34543692 | 2022 | Dysregulation of DPYSL2 expression by mTOR signaling in schizophrenia: Multi-level study of postmortem brain. | 6 |
| 34773219 | 2022 | Phosphorylation of CRMP2 by Cdk5 Negatively Regulates the Surface Delivery and Synaptic Function of AMPA Receptors. | 2 |
Citation
Dessen P
DPYSL2 (dihydropyrimidinase like 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-04-01
Online version: http://atlasgeneticsoncology.org/gene/50096/dpysl2
