Identity
HGNC
LOCATION
5q32
LOCUSID
ALIAS
CRMP-4,CRMP4,DRP-3,DRP3,LCRMP,ULIP,ULIP-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1809
MIM: 601168
HGNC: 3015
Ensembl: ENSG00000113657
Variants:
dbSNP: 1809
ClinVar: 1809
TCGA: ENSG00000113657
COSMIC: DPYSL3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| Semaphorin interactions | REACTOME | R-HSA-373755 |
| CRMPs in Sema3A signaling | REACTOME | R-HSA-399956 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37380971 | 2023 | Upregulation of dihydropyrimidinase-like 3 (DPYSL3) protein predicts poor prognosis in urothelial carcinoma. | 0 |
| 37380971 | 2023 | Upregulation of dihydropyrimidinase-like 3 (DPYSL3) protein predicts poor prognosis in urothelial carcinoma. | 0 |
| 33655336 | 2021 | Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium‑mediated cell signaling. | 2 |
| 33655336 | 2021 | Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium‑mediated cell signaling. | 2 |
| 31980687 | 2020 | Diabetes, an independent poor prognostic factor of non-B non-C hepatocellular carcinoma, correlates with dihydropyrimidinase-like 3 promoter methylation. | 6 |
| 32121246 | 2020 | Upregulation of Thr/Tyr kinase Increases the Cancer Progression by Neurotensin and Dihydropyrimidinase-Like 3 in Lung Cancer. | 15 |
| 31980687 | 2020 | Diabetes, an independent poor prognostic factor of non-B non-C hepatocellular carcinoma, correlates with dihydropyrimidinase-like 3 promoter methylation. | 6 |
| 32121246 | 2020 | Upregulation of Thr/Tyr kinase Increases the Cancer Progression by Neurotensin and Dihydropyrimidinase-Like 3 in Lung Cancer. | 15 |
| 28382925 | 2018 | Combined analysis of CRMP4 methylation levels and CAPRA-S score predicts metastasis and outcomes in prostate cancer patients. | 5 |
| 30498031 | 2018 | DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. | 27 |
| 28382925 | 2018 | Combined analysis of CRMP4 methylation levels and CAPRA-S score predicts metastasis and outcomes in prostate cancer patients. | 5 |
| 30498031 | 2018 | DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. | 27 |
| 29196732 | 2017 | Human CRMP4 mutation and disrupted Crmp4 expression in mice are associated with ASD characteristics and sexual dimorphism. | 9 |
| 29196732 | 2017 | Human CRMP4 mutation and disrupted Crmp4 expression in mice are associated with ASD characteristics and sexual dimorphism. | 9 |
| 27475326 | 2016 | Collapsin response mediator protein 4 isoforms (CRMP4a and CRMP4b) have opposite effects on cell proliferation, migration, and invasion in gastric cancer. | 15 |
Citation
Dessen P
DPYSL3 (dihydropyrimidinase like 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45599/dpysl3
