| Nomenclature |
|---|
| HGNC (Hugo) | DRD5 3026 |
| Cards |
|---|
| Entrez_Gene (NCBI) | DRD5 1816 dopamine receptor D5 |
| Aliases | DBDR; DRD1B; DRD1L2 |
| GeneCards (Weizmann) | DRD5 |
| Ensembl hg19 (Hinxton) | ENSG00000169676 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000169676 [Gene_View] ENSG00000169676 [Sequence] chr4:9781634-9784009 [Contig_View] DRD5 [Vega] |
| ICGC DataPortal | ENSG00000169676 |
| TCGA cBioPortal | DRD5 |
| AceView (NCBI) | DRD5 |
| Genatlas (Paris) | DRD5 |
| WikiGenes | 1816 |
| SOURCE (Princeton) | DRD5 |
| Genetics Home Reference (NIH) | DRD5 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | DRD5 - chr4:9781634-9784009 + 4p16.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | DRD5 - 4p16.1 [Description] (hg19-Feb_2009) |
| GoldenPath | DRD5 - 4p16.1 [CytoView hg19] DRD5 - 4p16.1 [CytoView hg38] |
| ImmunoBase | ENSG00000169676 |
| Mapping of homologs : NCBI | DRD5 [Mapview hg19] DRD5 [Mapview hg38] |
| OMIM | 126453 143465 606798 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK313897 AY136750 BC009748 |
| RefSeq transcript (Entrez) | NM_000798 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | DRD5 |
| Cluster EST : Unigene | Hs.380681 [ NCBI ] |
| CGAP (NCI) | Hs.380681 |
| Alternative Splicing Gallery | ENSG00000169676 |
| Gene Expression | DRD5 [ NCBI-GEO ] DRD5 [ EBI - ARRAY_EXPRESS ]
DRD5 [ SEEK ] DRD5 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | DRD5 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1816 |
| GTEX Portal (Tissue expression) | DRD5 |
| Human Protein Atlas | ENSG00000169676-DRD5 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P21918 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P21918 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P21918 |
| Splice isoforms : SwissVar | P21918 |
| PhosPhoSitePlus | P21918 |
| Domaine pattern : Prosite (Expaxy) | G_PROTEIN_RECEP_F1_1 (PS00237) G_PROTEIN_RECEP_F1_2 (PS50262) |
| Domains : Interpro (EBI) | Dopamine_D5_rcpt Dopamine_rcpt GPCR_Rhodpsn GPCR_Rhodpsn_7TM |
| Domain families : Pfam (Sanger) | 7tm_1 (PF00001) |
| Domain families : Pfam (NCBI) | pfam00001 |
| Domain families : Smart (EMBL) | 7TM_GPCR_Srsx (SM01381) |
| Conserved Domain (NCBI) | DRD5 |
| DMDM Disease mutations | 1816 |
| Blocks (Seattle) | DRD5 |
| Superfamily | P21918 |
| Human Protein Atlas [tissue] | ENSG00000169676-DRD5 [tissue] |
| Peptide Atlas | P21918 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P21918 |
| IntAct (EBI) | P21918 |
| FunCoup | ENSG00000169676 |
| BioGRID | DRD5 |
| STRING (EMBL) | DRD5 |
| ZODIAC | DRD5 |
| Ontologies - Pathways |
|---|
| QuickGO | P21918 |
| Ontology : AmiGO | dopamine neurotransmitter receptor activity, coupled via Gs dopamine neurotransmitter receptor activity, coupled via Gs synaptic transmission, dopaminergic G-protein alpha-subunit binding response to amphetamine regulation of systemic arterial blood pressure by vasopressin norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure dopamine neurotransmitter receptor activity plasma membrane plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cilium cellular calcium ion homeostasis G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway chemical synaptic transmission associative learning transmission of nerve impulse brush border membrane negative regulation of NAD(P)H oxidase activity dopamine binding dopamine binding wound healing response to cocaine positive regulation of adenylate cyclase activity negative regulation of blood pressure regulation of female receptivity sensitization phospholipase C-activating dopamine receptor signaling pathway ciliary membrane long-term synaptic depression cellular response to catecholamine stimulus reactive oxygen species metabolic process non-motile cilium |
| Ontology : EGO-EBI | dopamine neurotransmitter receptor activity, coupled via Gs dopamine neurotransmitter receptor activity, coupled via Gs synaptic transmission, dopaminergic G-protein alpha-subunit binding response to amphetamine regulation of systemic arterial blood pressure by vasopressin norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure dopamine neurotransmitter receptor activity plasma membrane plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cilium cellular calcium ion homeostasis G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway chemical synaptic transmission associative learning transmission of nerve impulse brush border membrane negative regulation of NAD(P)H oxidase activity dopamine binding dopamine binding wound healing response to cocaine positive regulation of adenylate cyclase activity negative regulation of blood pressure regulation of female receptivity sensitization phospholipase C-activating dopamine receptor signaling pathway ciliary membrane long-term synaptic depression cellular response to catecholamine stimulus reactive oxygen species metabolic process non-motile cilium |
| Pathways : KEGG | Calcium signaling pathway Neuroactive ligand-receptor interaction Dopaminergic synapse |
| NDEx Network | DRD5 |
| Atlas of Cancer Signalling Network | DRD5 |
| Wikipedia pathways | DRD5 |
| Orthology - Evolution |
|---|
| OrthoDB | 1816 |
| GeneTree (enSembl) | ENSG00000169676 |
| Phylogenetic Trees/Animal Genes : TreeFam | DRD5 |
| HOGENOM | P21918 |
| Homologs : HomoloGene | DRD5 |
| Homology/Alignments : Family Browser (UCSC) | DRD5 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | DRD5 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | DRD5 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | DRD5 |
| dbVar | DRD5 |
| ClinVar | DRD5 |
| 1000_Genomes | DRD5 |
| Exome Variant Server | DRD5 |
| ExAC (Exome Aggregation Consortium) | ENSG00000169676 |
| GNOMAD Browser | ENSG00000169676 |
| Varsome Browser | DRD5 |
| Genetic variants : HAPMAP | 1816 |
| Genomic Variants (DGV) | DRD5 [DGVbeta] |
| DECIPHER | DRD5 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | DRD5 |
| Mutations |
|---|
| ICGC Data Portal | DRD5 |
| TCGA Data Portal | DRD5 |
| Broad Tumor Portal | DRD5 |
| OASIS Portal | DRD5 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | DRD5 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | DRD5 |
| Mutations and Diseases : HGMD | DRD5 |
| BioMuta | search DRD5 |
| DgiDB (Drug Gene Interaction Database) | DRD5 |
| DoCM (Curated mutations) | DRD5 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | DRD5 (select a term) |
| intoGen | DRD5 |
| Cancer3D | DRD5(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 126453 143465 606798 |
| Orphanet | |
| DisGeNET | DRD5 |
| Medgen | DRD5 |
| Genetic Testing Registry | DRD5
|
| NextProt | P21918 [Medical] |
| TSGene | 1816 |
| GENETests | DRD5 |
| Target Validation | DRD5 |
| Huge Navigator |
DRD5 [HugePedia] |
| snp3D : Map Gene to Disease | 1816 |
| BioCentury BCIQ | DRD5 |
| ClinGen | DRD5 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1816 |
| Chemical/Pharm GKB Gene | PA148 |
| Clinical trial | DRD5 |
| Miscellaneous |
|---|
| canSAR (ICR) | DRD5 (select the gene name) |
| DataMed Index | DRD5 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 116 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | DRD5 |
| EVEX | DRD5 |
| GoPubMed | DRD5 |
| iHOP | DRD5 |
