DSPP (dentin sialophosphoprotein)

2003-05-01  

Identity

HGNC
LOCATION
4q22.1
LOCUSID
ALIAS
DFNA39,DGI1,DMP3,DPP,DSP

Other Information

Locus ID:

NCBI: 1834
MIM: 125485
HGNC: 3054
Ensembl: ENSG00000152591

Variants:

dbSNP: 1834
ClinVar: 1834
TCGA: ENSG00000152591
COSMIC: DSPP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152591ENST00000651931Q9NZW4

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
153293692004Expression of SIBLINGs and their partner MMPs in salivary glands.70
159549042005Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs).59
203671162010Dentin sialophosphoprotein in biomineralization.50
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45
153714332004Phosphophoryn regulates the gene expression and differentiation of NIH3T3, MC3T3-E1, and human mesenchymal stem cells via the integrin/MAPK signaling pathway.44
166795142006Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation.44
185218312008A comprehensive analysis of normal variation and disease-causing mutations in the human DSPP gene.37
118566452002Investigation of osteocalcin, osteonectin, and dentin sialophosphoprotein in developing human teeth.32
160146272005Dentin sialoprotein and dentin phosphoprotein overexpression during amelogenesis.27
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.27

Citation

Dessen P

DSPP (dentin sialophosphoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40368/dspp