Identity
HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
CDC8,PP3731,TMPK,TYMK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1841
MIM: 188345
HGNC: 3061
Ensembl: ENSG00000168393
Variants:
dbSNP: 1841
ClinVar: 1841
TCGA: ENSG00000168393
COSMIC: DTYMK
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451954 | zidovudine | Chemical | Pathway | associated | 22960662 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37358701 | 2023 | The evolving landscape of involvement of DTYMK enzymes in cancer. | 0 |
| 37358701 | 2023 | The evolving landscape of involvement of DTYMK enzymes in cancer. | 0 |
| 34918187 | 2022 | DTYMK is essential for genome integrity and neuronal survival. | 7 |
| 34918187 | 2022 | DTYMK is essential for genome integrity and neuronal survival. | 7 |
| 31887566 | 2020 | Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. | 17 |
| 31887566 | 2020 | Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. | 17 |
| 30199284 | 2019 | Thymidylate kinase is critical for DNA repair via ATM-dependent Tip60 complex formation. | 0 |
| 30447376 | 2019 | Insights into product release dynamics through structural analyses of thymidylate kinase. | 1 |
| 31271740 | 2019 | Deoxythymidylate kinase, DTYMK, is a novel gene for mitochondrial DNA depletion syndrome. | 13 |
| 30199284 | 2019 | Thymidylate kinase is critical for DNA repair via ATM-dependent Tip60 complex formation. | 0 |
| 30447376 | 2019 | Insights into product release dynamics through structural analyses of thymidylate kinase. | 1 |
| 31271740 | 2019 | Deoxythymidylate kinase, DTYMK, is a novel gene for mitochondrial DNA depletion syndrome. | 13 |
| 18413751 | 2008 | Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status. | 10 |
| 18413751 | 2008 | Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status. | 10 |
Citation
Dessen P
DTYMK (deoxythymidylate kinase)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50236/dtymk
