Identity
HGNC
LOCATION
15q21.1
LOCUSID
ALIAS
LNOX2,NOXEF2,P138-TOX,TDH6,THOX2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50506
MIM: 606759
HGNC: 13273
Ensembl: ENSG00000140279
Variants:
dbSNP: 50506
ClinVar: 50506
TCGA: ENSG00000140279
COSMIC: DUOX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140279 | ENST00000389039 | X6RAN8 |
| ENSG00000140279 | ENST00000603300 | Q9NRD8 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36607642 | 2023 | DUOX2 regulates secreted factors in virus-infected respiratory epithelial cells that contribute to neutrophil attraction and activation. | 1 |
| 37517801 | 2023 | Another Breach in the Wall: Impaired Epithelial DUOX2 Activity Fuels Metabolic Syndrome. | 0 |
| 36607642 | 2023 | DUOX2 regulates secreted factors in virus-infected respiratory epithelial cells that contribute to neutrophil attraction and activation. | 1 |
| 37517801 | 2023 | Another Breach in the Wall: Impaired Epithelial DUOX2 Activity Fuels Metabolic Syndrome. | 0 |
| 35507000 | 2022 | Mutational screening of the TPO and DUOX2 genes in Argentinian children with congenital hypothyroidism due to thyroid dyshormonogenesis. | 2 |
| 35960091 | 2022 | Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation. | 4 |
| 35507000 | 2022 | Mutational screening of the TPO and DUOX2 genes in Argentinian children with congenital hypothyroidism due to thyroid dyshormonogenesis. | 2 |
| 35960091 | 2022 | Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation. | 4 |
| 32531052 | 2021 | DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3. | 18 |
| 32803677 | 2021 | Identification and analyzes of DUOX2 mutations in two familial congenital hypothyroidism cases. | 1 |
| 33628596 | 2021 | A truncated protein product of the germline variant of the DUOX2 gene leads to adenomatous polyposis. | 4 |
| 33631011 | 2021 | Dual Oxidase System Genes Defects in Children With Congenital Hypothyroidism. | 4 |
| 33651715 | 2021 | DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk. | 24 |
| 33748270 | 2021 | DUOX2 As a Potential Prognostic Marker which Promotes Cell Motility and Proliferation in Pancreatic Cancer. | 3 |
| 34564849 | 2021 | Correlation of DUOX2 residual enzymatic activity with phenotype in congenital hypothyroidism caused by biallelic DUOX2 defects. | 2 |
Citation
Dessen P
DUOX2 (dual oxidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46154/duox2
