DUSP11 (dual specificity phosphatase 11)

2016-10-01  

Identity

HGNC
DUSP11
LOCATION
2p13.1
LOCUSID
8446
ALIAS
PIR1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8446
MIM: 603092
HGNC: 3066
Ensembl: ENSG00000144048

Variants:

dbSNP: 8446
ClinVar: 8446
TCGA: ENSG00000144048
COSMIC: DUSP11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144048ENST00000272444O75319
ENSG00000144048ENST00000443070O75319
ENSG00000144048ENST00000452812H7C0E6

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
277988492016DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs.15
296727162018miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11.10
244472652014Structure of human PIR1, an atypical dual-specificity phosphatase.9
282966242017DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells.8
300380172018RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.6
191206882009Isolation and characterization of DUSP11, a novel p53 target gene.4
291182702017Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells.4

Citation

Dessen P

DUSP11 (dual specificity phosphatase 11)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56384/dusp11