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DUSP9 (dual specificity phosphatase 9)

Identity

Alias_symbol (synonym)MKP-4
MKP4
Other alias
HGNC (Hugo) DUSP9
LocusID (NCBI) 1852
Atlas_Id 40379
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153642443 and ends at 153651326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DUSP9 (Xq28) / UBB (17p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DUSP9   3076
Cards
Entrez_Gene (NCBI)DUSP9  1852  dual specificity phosphatase 9
AliasesMKP-4; MKP4
GeneCards (Weizmann)DUSP9
Ensembl hg19 (Hinxton)ENSG00000130829 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130829 [Gene_View]  ENSG00000130829 [Sequence]  chrX:153642443-153651326 [Contig_View]  DUSP9 [Vega]
ICGC DataPortalENSG00000130829
TCGA cBioPortalDUSP9
AceView (NCBI)DUSP9
Genatlas (Paris)DUSP9
WikiGenes1852
SOURCE (Princeton)DUSP9
Genetics Home Reference (NIH)DUSP9
Genomic and cartography
GoldenPath hg38 (UCSC)DUSP9  -     chrX:153642443-153651326 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUSP9  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathDUSP9 - Xq28 [CytoView hg19]  DUSP9 - Xq28 [CytoView hg38]
ImmunoBaseENSG00000130829
Mapping of homologs : NCBIDUSP9 [Mapview hg19]  DUSP9 [Mapview hg38]
OMIM300134   
Gene and transcription
Genbank (Entrez)AI253132 AK314250 BC034936 BC042166 BC060837
RefSeq transcript (Entrez)NM_001318503 NM_001395
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUSP9
Cluster EST : UnigeneHs.744909 [ NCBI ]
CGAP (NCI)Hs.744909
Alternative Splicing GalleryENSG00000130829
Gene ExpressionDUSP9 [ NCBI-GEO ]   DUSP9 [ EBI - ARRAY_EXPRESS ]   DUSP9 [ SEEK ]   DUSP9 [ MEM ]
Gene Expression Viewer (FireBrowse)DUSP9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1852
GTEX Portal (Tissue expression)DUSP9
Human Protein AtlasENSG00000130829-DUSP9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99956   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99956  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99956
Splice isoforms : SwissVarQ99956
PhosPhoSitePlusQ99956
Domaine pattern : Prosite (Expaxy)RHODANESE_3 (PS50206)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP    MKP    Prot-tyrosine_phosphatase-like    Rhodanese-like_dom    Rhodanese-like_dom_sf    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)    Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam00782    pfam00581   
Domain families : Smart (EMBL)DSPc (SM00195)  RHOD (SM00450)  
Conserved Domain (NCBI)DUSP9
DMDM Disease mutations1852
Blocks (Seattle)DUSP9
PDB (RSDB)2HXP    3LJ8   
PDB Europe2HXP    3LJ8   
PDB (PDBSum)2HXP    3LJ8   
PDB (IMB)2HXP    3LJ8   
Structural Biology KnowledgeBase2HXP    3LJ8   
SCOP (Structural Classification of Proteins)2HXP    3LJ8   
CATH (Classification of proteins structures)2HXP    3LJ8   
SuperfamilyQ99956
Human Protein Atlas [tissue]ENSG00000130829-DUSP9 [tissue]
Peptide AtlasQ99956
HPRD02136
IPIIPI00294486   IPI00384224   
Protein Interaction databases
DIP (DOE-UCLA)Q99956
IntAct (EBI)Q99956
FunCoupENSG00000130829
BioGRIDDUSP9
STRING (EMBL)DUSP9
ZODIACDUSP9
Ontologies - Pathways
QuickGOQ99956
Ontology : AmiGOMAPK cascade  activation of MAPK activity  inactivation of MAPK activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  protein dephosphorylation  JNK cascade  protein tyrosine/serine/threonine phosphatase activity  MAP kinase tyrosine/serine/threonine phosphatase activity  peptidyl-tyrosine dephosphorylation  
Ontology : EGO-EBIMAPK cascade  activation of MAPK activity  inactivation of MAPK activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  cytosol  cytosol  protein dephosphorylation  JNK cascade  protein tyrosine/serine/threonine phosphatase activity  MAP kinase tyrosine/serine/threonine phosphatase activity  peptidyl-tyrosine dephosphorylation  
Pathways : KEGGMAPK signaling pathway   
NDEx NetworkDUSP9
Atlas of Cancer Signalling NetworkDUSP9
Wikipedia pathwaysDUSP9
Orthology - Evolution
OrthoDB1852
GeneTree (enSembl)ENSG00000130829
Phylogenetic Trees/Animal Genes : TreeFamDUSP9
HOGENOMQ99956
Homologs : HomoloGeneDUSP9
Homology/Alignments : Family Browser (UCSC)DUSP9
Gene fusions - Rearrangements
Fusion : QuiverDUSP9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUSP9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUSP9
dbVarDUSP9
ClinVarDUSP9
1000_GenomesDUSP9 
Exome Variant ServerDUSP9
ExAC (Exome Aggregation Consortium)ENSG00000130829
GNOMAD BrowserENSG00000130829
Varsome BrowserDUSP9
Genetic variants : HAPMAP1852
Genomic Variants (DGV)DUSP9 [DGVbeta]
DECIPHERDUSP9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUSP9 
Mutations
ICGC Data PortalDUSP9 
TCGA Data PortalDUSP9 
Broad Tumor PortalDUSP9
OASIS PortalDUSP9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUSP9  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDUSP9
Mutations and Diseases : HGMDDUSP9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DUSP9
DgiDB (Drug Gene Interaction Database)DUSP9
DoCM (Curated mutations)DUSP9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUSP9 (select a term)
intoGenDUSP9
Cancer3DDUSP9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300134   
Orphanet
DisGeNETDUSP9
MedgenDUSP9
Genetic Testing Registry DUSP9
NextProtQ99956 [Medical]
TSGene1852
GENETestsDUSP9
Target ValidationDUSP9
Huge Navigator DUSP9 [HugePedia]
snp3D : Map Gene to Disease1852
BioCentury BCIQDUSP9
ClinGenDUSP9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1852
Chemical/Pharm GKB GenePA27533
Clinical trialDUSP9
Miscellaneous
canSAR (ICR)DUSP9 (select the gene name)
DataMed IndexDUSP9
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUSP9
EVEXDUSP9
GoPubMedDUSP9
iHOPDUSP9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:41:14 CET 2019
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