Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DUT (deoxyuridine triphosphatase)

Identity

Alias_namesdUTP pyrophosphatase
Alias_symbol (synonym)dUTPase
Other alias
HGNC (Hugo) DUT
LocusID (NCBI) 1854
Atlas_Id 43233
Location 15q21.1  [Link to chromosome band 15q21]
Location_base_pair Starts at 48332168 and ends at 48343373 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DUT (15q21.1) / DUT (15q21.1)DUT (15q21.1) / TPT1 (13q14.13)TPT1 (13q14.13) / DUT (15q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DUT   3078
Cards
Entrez_Gene (NCBI)DUT  1854  deoxyuridine triphosphatase
AliasesdUTPase
GeneCards (Weizmann)DUT
Ensembl hg19 (Hinxton)ENSG00000128951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128951 [Gene_View]  ENSG00000128951 [Sequence]  chr15:48332168-48343373 [Contig_View]  DUT [Vega]
ICGC DataPortalENSG00000128951
TCGA cBioPortalDUT
AceView (NCBI)DUT
Genatlas (Paris)DUT
WikiGenes1854
SOURCE (Princeton)DUT
Genetics Home Reference (NIH)DUT
Genomic and cartography
GoldenPath hg38 (UCSC)DUT  -     chr15:48332168-48343373 +  15q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DUT  -     15q21.1   [Description]    (hg19-Feb_2009)
GoldenPathDUT - 15q21.1 [CytoView hg19]  DUT - 15q21.1 [CytoView hg38]
ImmunoBaseENSG00000128951
Mapping of homologs : NCBIDUT [Mapview hg19]  DUT [Mapview hg38]
OMIM601266   
Gene and transcription
Genbank (Entrez)AB049113 AK000629 AK291515 AK298464 AK312122
RefSeq transcript (Entrez)NM_001025248 NM_001025249 NM_001330286 NM_001948
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DUT
Cluster EST : UnigeneHs.527980 [ NCBI ]
CGAP (NCI)Hs.527980
Alternative Splicing GalleryENSG00000128951
Gene ExpressionDUT [ NCBI-GEO ]   DUT [ EBI - ARRAY_EXPRESS ]   DUT [ SEEK ]   DUT [ MEM ]
Gene Expression Viewer (FireBrowse)DUT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1854
GTEX Portal (Tissue expression)DUT
Human Protein AtlasENSG00000128951-DUT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP33316   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP33316  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP33316
Splice isoforms : SwissVarP33316
Catalytic activity : Enzyme3.6.1.23 [ Enzyme-Expasy ]   3.6.1.233.6.1.23 [ IntEnz-EBI ]   3.6.1.23 [ BRENDA ]   3.6.1.23 [ KEGG ]   
PhosPhoSitePlusP33316
Domains : Interpro (EBI)dUTPase-like    dUTPase-like_sf    dUTPase_1    dUTPase_trimeric   
Domain families : Pfam (Sanger)dUTPase (PF00692)   
Domain families : Pfam (NCBI)pfam00692   
Conserved Domain (NCBI)DUT
DMDM Disease mutations1854
Blocks (Seattle)DUT
PDB (RSDB)1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
PDB Europe1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
PDB (PDBSum)1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
PDB (IMB)1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
Structural Biology KnowledgeBase1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
SCOP (Structural Classification of Proteins)1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
CATH (Classification of proteins structures)1Q5H    1Q5U    2HQU    3ARA    3ARN    3EHW    4MZ5    4MZ6    5H4J   
SuperfamilyP33316
Human Protein Atlas [tissue]ENSG00000128951-DUT [tissue]
Peptide AtlasP33316
HPRD03165
IPIIPI00375015   IPI00749113   IPI00013679   IPI00794545   
Protein Interaction databases
DIP (DOE-UCLA)P33316
IntAct (EBI)P33316
FunCoupENSG00000128951
BioGRIDDUT
STRING (EMBL)DUT
ZODIACDUT
Ontologies - Pathways
QuickGOP33316
Ontology : AmiGOmagnesium ion binding  RNA binding  dUTP diphosphatase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  nucleobase-containing compound metabolic process  dUMP biosynthetic process  dUMP biosynthetic process  DNA replication  nucleobase-containing small molecule interconversion  dUTP catabolic process  extracellular exosome  
Ontology : EGO-EBImagnesium ion binding  RNA binding  dUTP diphosphatase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  nucleobase-containing compound metabolic process  dUMP biosynthetic process  dUMP biosynthetic process  DNA replication  nucleobase-containing small molecule interconversion  dUTP catabolic process  extracellular exosome  
Pathways : KEGGPyrimidine metabolism   
NDEx NetworkDUT
Atlas of Cancer Signalling NetworkDUT
Wikipedia pathwaysDUT
Orthology - Evolution
OrthoDB1854
GeneTree (enSembl)ENSG00000128951
Phylogenetic Trees/Animal Genes : TreeFamDUT
HOGENOMP33316
Homologs : HomoloGeneDUT
Homology/Alignments : Family Browser (UCSC)DUT
Gene fusions - Rearrangements
Fusion : QuiverDUT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDUT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DUT
dbVarDUT
ClinVarDUT
1000_GenomesDUT 
Exome Variant ServerDUT
ExAC (Exome Aggregation Consortium)ENSG00000128951
GNOMAD BrowserENSG00000128951
Varsome BrowserDUT
Genetic variants : HAPMAP1854
Genomic Variants (DGV)DUT [DGVbeta]
DECIPHERDUT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDUT 
Mutations
ICGC Data PortalDUT 
TCGA Data PortalDUT 
Broad Tumor PortalDUT
OASIS PortalDUT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDUT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDUT
Mutations and Diseases : HGMDDUT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DUT
DgiDB (Drug Gene Interaction Database)DUT
DoCM (Curated mutations)DUT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DUT (select a term)
intoGenDUT
Cancer3DDUT(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601266   
Orphanet
DisGeNETDUT
MedgenDUT
Genetic Testing Registry DUT
NextProtP33316 [Medical]
TSGene1854
GENETestsDUT
Target ValidationDUT
Huge Navigator DUT [HugePedia]
snp3D : Map Gene to Disease1854
BioCentury BCIQDUT
ClinGenDUT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1854
Chemical/Pharm GKB GenePA151
Clinical trialDUT
Miscellaneous
canSAR (ICR)DUT (select the gene name)
DataMed IndexDUT
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDUT
EVEXDUT
GoPubMedDUT
iHOPDUT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:41:14 CET 2019
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