DZIP1 (DAZ interacting zinc finger protein 1)

2017-08-01  

Identity

HGNC
LOCATION
13q32.1
LOCUSID
ALIAS
DZIP,DZIPt1,MVP3,SPGF47
FUSION GENES

Other Information

Locus ID:

NCBI: 22873
MIM: 608671
HGNC: 20908
Ensembl: ENSG00000134874

Variants:

dbSNP: 22873
ClinVar: 22873
TCGA: ENSG00000134874
COSMIC: DZIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134874ENST00000347108Q86YF9
ENSG00000134874ENST00000361156Q86YF9
ENSG00000134874ENST00000361396Q86YF9
ENSG00000134874ENST00000376829Q86YF9
ENSG00000134874ENST00000466569Q86YF9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by HedgehogREACTOMER-HSA-5358351
Hedgehog 'on' stateREACTOMER-HSA-5632684

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
150811132004Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.20
150811132004Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.20
218786432011The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.10
279799672017DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.7
240727102013Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling.5
249936352014Ribonomic analysis of human DZIP1 reveals its involvement in ribonucleoprotein complexes and stress granules.2
280855392017Mutations in DZIP1 and XYLT1 are associated with nonsyndromic early onset high myopia in the Korean population.1

Citation

Dessen P

DZIP1 (DAZ interacting zinc finger protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56926/dzip1