ECPAS (Ecm29 proteasome adaptor and scaffold)

2014-05-01  

Identity

HGNC
ECPAS
LOCATION
9q31.3
LOCUSID
23392
ALIAS
ECM29,KIAA0368
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23392
MIM: 616694
HGNC: 29020
Ensembl: ENSG00000136813

Variants:

dbSNP: 23392
ClinVar: 23392
TCGA: ENSG00000136813
COSMIC: ECPAS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136813ENST00000259335J3KN16
ENSG00000136813ENST00000338205Q5VYK3
ENSG00000136813ENST00000374383F6XAQ5
ENSG00000136813ENST00000602447R4GMY1
ENSG00000136813ENST00000602978R4GMY3

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
206827912010A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.33
154964062004Characterization of mammalian Ecm29, a 26 S proteasome-associated protein that localizes to the nucleus and membrane vesicles.29
288216112017The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress.24
240846482013Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling.8
268027432016KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition.5

Citation

Dessen P

ECPAS (Ecm29 proteasome adaptor and scaffold)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53903/ecpas