ECRG4 (ECRG4 augurin precursor)

2003-06-01  

Identity

HGNC
LOCATION
2q12.2
LOCUSID
ALIAS
C2orf40

Other Information

Locus ID:

NCBI: 84417
MIM: 611752
HGNC: 24642
Ensembl: ENSG00000119147

Variants:

dbSNP: 84417
ClinVar: 84417
TCGA: ENSG00000119147
COSMIC: ECRG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119147ENST00000238044Q9H1Z8
ENSG00000119147ENST00000409944B8ZZE5
ENSG00000119147ENST00000437659C9JRR0

References

Pubmed IDYearTitleCitations
221107082011Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer.53
195219892009Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo.43
200179172009ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma.34
128002182003Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma.32
177863632007Expression of ECRG4 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma.29
205981622010Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion.29
212883672011A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma.22
219354312011Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury.21
237708142013C2ORF40 suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes.18
225266222012Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4.16

Citation

Dessen P

ECRG4 (ECRG4 augurin precursor)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40399/ecrg4