| Nomenclature |
|---|
| HGNC (Hugo) | EGR4 3241 |
| Cards |
|---|
| Entrez_Gene (NCBI) | EGR4 1961 early growth response 4 |
| Aliases | AT133; NGFI-C; NGFIC; PAT133 |
| GeneCards (Weizmann) | EGR4 |
| Ensembl hg19 (Hinxton) | ENSG00000135625 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000135625 [Gene_View] ENSG00000135625 [Sequence] chr2:73290929-73293701 [Contig_View] EGR4 [Vega] |
| ICGC DataPortal | ENSG00000135625 |
| TCGA cBioPortal | EGR4 |
| AceView (NCBI) | EGR4 |
| Genatlas (Paris) | EGR4 |
| WikiGenes | 1961 |
| SOURCE (Princeton) | EGR4 |
| Genetics Home Reference (NIH) | EGR4 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | EGR4 - chr2:73290929-73293701 - 2p13.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | EGR4 - 2p13.2 [Description] (hg19-Feb_2009) |
| GoldenPath | EGR4 - 2p13.2 [CytoView hg19] EGR4 - 2p13.2 [CytoView hg38] |
| ImmunoBase | ENSG00000135625 |
| Mapping of homologs : NCBI | EGR4 [Mapview hg19] EGR4 [Mapview hg38] |
| OMIM | 128992 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK314154 BC034462 BC136252 BC143379 BX091371 |
| RefSeq transcript (Entrez) | NM_001965 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | EGR4 |
| Cluster EST : Unigene | Hs.3052 [ NCBI ] |
| CGAP (NCI) | Hs.3052 |
| Alternative Splicing Gallery | ENSG00000135625 |
| Gene Expression | EGR4 [ NCBI-GEO ] EGR4 [ EBI - ARRAY_EXPRESS ]
EGR4 [ SEEK ] EGR4 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | EGR4 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1961 |
| GTEX Portal (Tissue expression) | EGR4 |
| Human Protein Atlas | ENSG00000135625-EGR4 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q05215 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q05215 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q05215 |
| Splice isoforms : SwissVar | Q05215 |
| PhosPhoSitePlus | Q05215 |
| Domaine pattern : Prosite (Expaxy) | ZINC_FINGER_C2H2_1 (PS00028) ZINC_FINGER_C2H2_2 (PS50157) |
| Domains : Interpro (EBI) | Znf_C2H2_sf Znf_C2H2_type |
| Domain families : Pfam (Sanger) | |
| Domain families : Pfam (NCBI) | |
| Domain families : Smart (EMBL) | ZnF_C2H2 (SM00355) |
| Conserved Domain (NCBI) | EGR4 |
| DMDM Disease mutations | 1961 |
| Blocks (Seattle) | EGR4 |
| Superfamily | Q05215 |
| Human Protein Atlas [tissue] | ENSG00000135625-EGR4 [tissue] |
| Peptide Atlas | Q05215 |
| HPRD | 00550 |
| IPI | IPI00289101 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q05215 |
| IntAct (EBI) | Q05215 |
| FunCoup | ENSG00000135625 |
| BioGRID | EGR4 |
| STRING (EMBL) | EGR4 |
| ZODIAC | EGR4 |
| Ontologies - Pathways |
|---|
| QuickGO | Q05215 |
| Ontology : AmiGO | RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus regulation of transcription by RNA polymerase II positive regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cellular response to growth factor stimulus |
| Ontology : EGO-EBI | RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus regulation of transcription by RNA polymerase II positive regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cellular response to growth factor stimulus |
| NDEx Network | EGR4 |
| Atlas of Cancer Signalling Network | EGR4 |
| Wikipedia pathways | EGR4 |
| Orthology - Evolution |
|---|
| OrthoDB | 1961 |
| GeneTree (enSembl) | ENSG00000135625 |
| Phylogenetic Trees/Animal Genes : TreeFam | EGR4 |
| HOGENOM | Q05215 |
| Homologs : HomoloGene | EGR4 |
| Homology/Alignments : Family Browser (UCSC) | EGR4 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | EGR4 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | EGR4 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | EGR4 |
| dbVar | EGR4 |
| ClinVar | EGR4 |
| 1000_Genomes | EGR4 |
| Exome Variant Server | EGR4 |
| ExAC (Exome Aggregation Consortium) | ENSG00000135625 |
| GNOMAD Browser | ENSG00000135625 |
| Varsome Browser | EGR4 |
| Genetic variants : HAPMAP | 1961 |
| Genomic Variants (DGV) | EGR4 [DGVbeta] |
| DECIPHER | EGR4 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | EGR4 |
| Mutations |
|---|
| ICGC Data Portal | EGR4 |
| TCGA Data Portal | EGR4 |
| Broad Tumor Portal | EGR4 |
| OASIS Portal | EGR4 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | EGR4 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | EGR4 |
| Mutations and Diseases : HGMD | EGR4 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search EGR4 |
| DgiDB (Drug Gene Interaction Database) | EGR4 |
| DoCM (Curated mutations) | EGR4 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | EGR4 (select a term) |
| intoGen | EGR4 |
| Cancer3D | EGR4(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 128992 |
| Orphanet | |
| DisGeNET | EGR4 |
| Medgen | EGR4 |
| Genetic Testing Registry | EGR4
|
| NextProt | Q05215 [Medical] |
| TSGene | 1961 |
| GENETests | EGR4 |
| Target Validation | EGR4 |
| Huge Navigator |
EGR4 [HugePedia] |
| snp3D : Map Gene to Disease | 1961 |
| BioCentury BCIQ | EGR4 |
| ClinGen | EGR4 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1961 |
| Chemical/Pharm GKB Gene | PA27676 |
| Clinical trial | EGR4 |
| Miscellaneous |
|---|
| canSAR (ICR) | EGR4 (select the gene name) |
| DataMed Index | EGR4 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 18 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | EGR4 |
| EVEX | EGR4 |
| GoPubMed | EGR4 |
| iHOP | EGR4 |
