EGR4 (early growth response 4)

2016-10-01  

Identity

HGNC
LOCATION
2p13.2
LOCUSID
ALIAS
AT133,NGFI-C,NGFIC,PAT133

Other Information

Locus ID:

NCBI: 1961
MIM: 128992
HGNC: 3241
Ensembl: ENSG00000135625

Variants:

dbSNP: 1961
ClinVar: 1961
TCGA: ENSG00000135625
COSMIC: EGR4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135625ENST00000436467A0A0C4DG96
ENSG00000135625ENST00000545030Q05215

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198289382009EGR4 is a master gene responsible for fertility in cryptorchidism.12
254118512014Early growth response 4 is involved in cell proliferation of small cell lung cancer through transcriptional activation of its downstream genes.11
201446772010No association between EGR gene family polymorphisms and schizophrenia in the Chinese population.5
226917142012Genetic and functional analyses of early growth response (EGR) family genes in schizophrenia.5
305562832019A positive feedback loop between ZNF205-AS1 and EGR4 promotes non-small cell lung cancer growth.4
284648462017Sequence variations of the EGR4 gene in Korean men with spermatogenesis impairment.0

Citation

Dessen P

EGR4 (early growth response 4)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56309/egr4