EHD4 (EH domain containing 4)

2014-11-01  

Identity

HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
PAST4
FUSION GENES

Other Information

Locus ID:

NCBI: 30844
MIM: 605892
HGNC: 3245
Ensembl: ENSG00000103966

Variants:

dbSNP: 30844
ClinVar: 30844
TCGA: ENSG00000103966
COSMIC: EHD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103966ENST00000220325Q9H223
ENSG00000103966ENST00000220325A0A024R9N6

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
183314522008A role for EHD4 in the regulation of early endosomal transport.67
204891642010EH domain proteins regulate cardiac membrane protein targeting.41
211873872011Trk retrograde signaling requires persistent, Pincher-directed endosomes.27
240195282013Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.27
233256862013Comparative proteomic analysis of HIV-1 particles reveals a role for Ezrin and EHD4 in the Nef-dependent increase of virus infectivity.19

Citation

Dessen P

EHD4 (EH domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62763/ehd4