Identity
HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
EHMT1-IT1,EUHMTASE1,Eu-HMTase1,FP13812,GLP,GLP1,KLEFS1,KMT1D
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79813
MIM: 607001
HGNC: 24650
Ensembl: ENSG00000181090
Variants:
dbSNP: 79813
ClinVar: 79813
TCGA: ENSG00000181090
COSMIC: EHMT1
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37257768 | 2023 | Cell consequences of loss of function of the epigenetic factor EHMT1. | 1 |
| 37663929 | 2023 | Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression. | 1 |
| 37894922 | 2023 | Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma. | 1 |
| 37257768 | 2023 | Cell consequences of loss of function of the epigenetic factor EHMT1. | 1 |
| 37663929 | 2023 | Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression. | 1 |
| 37894922 | 2023 | Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma. | 1 |
| 34897678 | 2022 | EHMT1 promotes tumor progression and maintains stemness by regulating ALDH1A1 expression in alveolar rhabdomyosarcoma. | 0 |
| 34954891 | 2022 | EHMT1/EHMT2 in EMT, cancer stemness and drug resistance: emerging evidence and mechanisms. | 20 |
| 34897678 | 2022 | EHMT1 promotes tumor progression and maintains stemness by regulating ALDH1A1 expression in alveolar rhabdomyosarcoma. | 0 |
| 34954891 | 2022 | EHMT1/EHMT2 in EMT, cancer stemness and drug resistance: emerging evidence and mechanisms. | 20 |
| 33283949 | 2021 | Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer. | 16 |
| 34214254 | 2021 | EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression. | 15 |
| 34265435 | 2021 | Clinical phenotypes and molecular findings in ten Chinese patients with Kleefstra Syndrome Type 1 due to EHMT1 defects. | 1 |
| 34357686 | 2021 | Kleefstra syndrome: Recurrence in siblings due to a paternal mosaic mutation. | 0 |
| 34588438 | 2021 | SPOP mutation induces DNA methylation via stabilizing GLP/G9a. | 17 |
Citation
Dessen P
EHMT1 (euchromatic histone lysine methyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-10-01
Online version: http://atlasgeneticsoncology.org/gene/51162/ehmt1
