Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EIF2S3B (eukaryotic translation initiation factor 2 subunit gamma B)

Identity

Other aliasEIF2S3L
eIF-2gA
eIF2gA
HGNC (Hugo) EIF2S3B
LocusID (NCBI) 255308
Atlas_Id 80324
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10505893 and ends at 10507988 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)EIF2S3B   43863
Cards
Entrez_Gene (NCBI)EIF2S3B  255308  eukaryotic translation initiation factor 2 subunit gamma B
AliasesEIF2S3L; eIF-2gA; eIF2gA
GeneCards (Weizmann)EIF2S3B
Ensembl hg19 (Hinxton)ENSG00000180574 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180574 [Gene_View]  ENSG00000180574 [Sequence]  chr12:10505893-10507988 [Contig_View]  EIF2S3B [Vega]
ICGC DataPortalENSG00000180574
TCGA cBioPortalEIF2S3B
AceView (NCBI)EIF2S3B
Genatlas (Paris)EIF2S3B
WikiGenes255308
SOURCE (Princeton)EIF2S3B
Genetics Home Reference (NIH)EIF2S3B
Genomic and cartography
GoldenPath hg38 (UCSC)EIF2S3B  -     chr12:10505893-10507988 +  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EIF2S3B  -     12p13.2   [Description]    (hg19-Feb_2009)
GoldenPathEIF2S3B - 12p13.2 [CytoView hg19]  EIF2S3B - 12p13.2 [CytoView hg38]
ImmunoBaseENSG00000180574
Mapping of homologs : NCBIEIF2S3B [Mapview hg19]  EIF2S3B [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC087847 DB461648 DB527071
RefSeq transcript (Entrez)NM_001357731 NM_001357734
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EIF2S3B
Cluster EST : UnigeneHs.547382 [ NCBI ]
CGAP (NCI)Hs.547382
Alternative Splicing GalleryENSG00000180574
Gene ExpressionEIF2S3B [ NCBI-GEO ]   EIF2S3B [ EBI - ARRAY_EXPRESS ]   EIF2S3B [ SEEK ]   EIF2S3B [ MEM ]
Gene Expression Viewer (FireBrowse)EIF2S3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255308
GTEX Portal (Tissue expression)EIF2S3B
Human Protein AtlasENSG00000180574-EIF2S3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2VIR3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2VIR3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2VIR3
Splice isoforms : SwissVarQ2VIR3
PhosPhoSitePlusQ2VIR3
Domaine pattern : Prosite (Expaxy)G_TR_2 (PS51722)   
Domains : Interpro (EBI)EFTu-like_2    P-loop_NTPase    TF_GTP-bd_dom    TIF2_gsu_C    Transl_B-barrel_sf    Transl_elong_EF1A/Init_IF2_C   
Domain families : Pfam (Sanger)eIF2_C (PF09173)    GTP_EFTU (PF00009)    GTP_EFTU_D2 (PF03144)   
Domain families : Pfam (NCBI)pfam09173    pfam00009    pfam03144   
Conserved Domain (NCBI)EIF2S3B
DMDM Disease mutations255308
Blocks (Seattle)EIF2S3B
SuperfamilyQ2VIR3
Human Protein Atlas [tissue]ENSG00000180574-EIF2S3B [tissue]
Peptide AtlasQ2VIR3
Protein Interaction databases
DIP (DOE-UCLA)Q2VIR3
IntAct (EBI)Q2VIR3
FunCoupENSG00000180574
BioGRIDEIF2S3B
STRING (EMBL)EIF2S3B
ZODIACEIF2S3B
Ontologies - Pathways
QuickGOQ2VIR3
Ontology : AmiGOtRNA binding  formation of translation preinitiation complex  translation initiation factor activity  GTPase activity  GTP binding  cytoplasm  cytosol  eukaryotic translation initiation factor 2 complex  positive regulation of translational fidelity  
Ontology : EGO-EBItRNA binding  formation of translation preinitiation complex  translation initiation factor activity  GTPase activity  GTP binding  cytoplasm  cytosol  eukaryotic translation initiation factor 2 complex  positive regulation of translational fidelity  
NDEx NetworkEIF2S3B
Atlas of Cancer Signalling NetworkEIF2S3B
Wikipedia pathwaysEIF2S3B
Orthology - Evolution
OrthoDB255308
GeneTree (enSembl)ENSG00000180574
Phylogenetic Trees/Animal Genes : TreeFamEIF2S3B
HOGENOMQ2VIR3
Homologs : HomoloGeneEIF2S3B
Homology/Alignments : Family Browser (UCSC)EIF2S3B
Gene fusions - Rearrangements
Fusion : QuiverEIF2S3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEIF2S3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EIF2S3B
dbVarEIF2S3B
ClinVarEIF2S3B
1000_GenomesEIF2S3B 
Exome Variant ServerEIF2S3B
ExAC (Exome Aggregation Consortium)ENSG00000180574
GNOMAD BrowserENSG00000180574
Varsome BrowserEIF2S3B
Genetic variants : HAPMAP255308
Genomic Variants (DGV)EIF2S3B [DGVbeta]
DECIPHEREIF2S3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEIF2S3B 
Mutations
ICGC Data PortalEIF2S3B 
TCGA Data PortalEIF2S3B 
Broad Tumor PortalEIF2S3B
OASIS PortalEIF2S3B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDEIF2S3B
BioMutasearch EIF2S3B
DgiDB (Drug Gene Interaction Database)EIF2S3B
DoCM (Curated mutations)EIF2S3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EIF2S3B (select a term)
intoGenEIF2S3B
Cancer3DEIF2S3B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETEIF2S3B
MedgenEIF2S3B
Genetic Testing Registry EIF2S3B
NextProtQ2VIR3 [Medical]
TSGene255308
GENETestsEIF2S3B
Target ValidationEIF2S3B
Huge Navigator EIF2S3B [HugePedia]
snp3D : Map Gene to Disease255308
BioCentury BCIQEIF2S3B
ClinGenEIF2S3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD255308
Clinical trialEIF2S3B
Miscellaneous
canSAR (ICR)EIF2S3B (select the gene name)
DataMed IndexEIF2S3B
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEIF2S3B
EVEXEIF2S3B
GoPubMedEIF2S3B
iHOPEIF2S3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Sep 3 15:26:37 CEST 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.