EIF3M (eukaryotic translation initiation factor 3 subunit M)

2011-03-01  

Identity

HGNC
LOCATION
11p13
LOCUSID
ALIAS
B5,GA17,PCID1,TANGO7,hfl-B5
FUSION GENES

Other Information

Locus ID:

NCBI: 10480
MIM: 609641
HGNC: 24460
Ensembl: ENSG00000149100

Variants:

dbSNP: 10480
ClinVar: 10480
TCGA: ENSG00000149100
COSMIC: EIF3M

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149100ENST00000323213J3KNJ2
ENSG00000149100ENST00000524711E9PRI2
ENSG00000149100ENST00000524896Q7L2H7
ENSG00000149100ENST00000525782E9PRY0
ENSG00000149100ENST00000526267H0YCQ8
ENSG00000149100ENST00000531120Q7L2H7
ENSG00000149100ENST00000531921E7ESM3
ENSG00000149100ENST00000532444E9PSB3
ENSG00000149100ENST00000533439E9PN86

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
Formation of the ternary complex, and subsequently, the 43S complexREACTOMER-HSA-72695
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SREACTOMER-HSA-72662
Translation initiation complex formationREACTOMER-HSA-72649
Ribosomal scanning and start codon recognitionREACTOMER-HSA-72702
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
Gene ExpressionREACTOMER-HSA-74160

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208383792011eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer.25
220229722011A minor isoform of the human RNA polymerase II subunit hRPB11 (POLR2J) interacts with several components of the translation initiation factor eIF3.11
208383792011eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer.25
220229722011A minor isoform of the human RNA polymerase II subunit hRPB11 (POLR2J) interacts with several components of the translation initiation factor eIF3.11
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206764072010HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206764072010HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target.7
194836762009Genome-wide silencing in Drosophila captures conserved apoptotic effectors.24
194836762009Genome-wide silencing in Drosophila captures conserved apoptotic effectors.24
159198982005A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins.15
159198992005The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection.7
159198982005A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins.15
159198992005The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection.7

Citation

Dessen P

EIF3M (eukaryotic translation initiation factor 3 subunit M)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52139/eif3m