Identity
HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
4E-LP,4EHP,EIF4EL3,IF4e,h4EHP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9470
MIM: 605895
HGNC: 3293
Ensembl: ENSG00000135930
Variants:
dbSNP: 9470
ClinVar: 9470
TCGA: ENSG00000135930
COSMIC: EIF4E2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36840945 | 2023 | METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2. | 14 |
| 36840945 | 2023 | METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2. | 14 |
| 33581076 | 2021 | microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP. | 14 |
| 33785306 | 2021 | High EIF4E2 expression is an independent prognostic risk factor for poor overall survival and recurrence-free survival in uveal melanoma. | 3 |
| 34665823 | 2021 | Translational repression of NMD targets by GIGYF2 and EIF4E2. | 17 |
| 33581076 | 2021 | microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP. | 14 |
| 33785306 | 2021 | High EIF4E2 expression is an independent prognostic risk factor for poor overall survival and recurrence-free survival in uveal melanoma. | 3 |
| 34665823 | 2021 | Translational repression of NMD targets by GIGYF2 and EIF4E2. | 17 |
| 32726578 | 2020 | GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. | 81 |
| 33053355 | 2020 | 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. | 27 |
| 32726578 | 2020 | GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. | 81 |
| 33053355 | 2020 | 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. | 27 |
| 28942592 | 2018 | Major splice variants and multiple polyadenylation site utilization in mRNAs encoding human translation initiation factors eIF4E1 and eIF4E3 regulate the translational regulators? | 4 |
| 28991229 | 2018 | Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion. | 18 |
| 29412140 | 2018 | Translational control of ERK signaling through miRNA/4EHP-directed silencing. | 23 |
Citation
Dessen P
EIF4E2 (eukaryotic translation initiation factor 4E family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52997/eif4e2
