ELMO3 (engulfment and cell motility 3)

2016-06-01  

Identity

HGNC
ELMO3
LOCATION
16q22.1
LOCUSID
79767
ALIAS
CED-12,CED12,ELMO-3

Other Information

Locus ID:

NCBI: 79767
MIM: 606422
HGNC: 17289
Ensembl: ENSG00000102890

Variants:

dbSNP: 79767
ClinVar: 79767
TCGA: ENSG00000102890
COSMIC: ELMO3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102890ENST00000360833F8W9E7
ENSG00000102890ENST00000393997Q96BJ8
ENSG00000102890ENST00000477898Q96BJ8
ENSG00000102890ENST00000571587I3L4D1
ENSG00000102890ENST00000652269Q96BJ8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ShigellosisKEGGhsa05131
Bacterial invasion of epithelial cellsKEGGko05100
Bacterial invasion of epithelial cellsKEGGhsa05100

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
201277202010Control of intestinal promoter activity of the cellular migratory regulator gene ELMO3 by CDX2 and SP1.11
261912572015ELMO3 is a novel biomarker for diagnosis and prognosis of non-small cell lung cancer.8
279992682016Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.6
280396092017ELMO3 expression indicates a poor prognosis in head and neck squamous cell carcinoma - a short report.5
303746202019ELMO3 - a Negative Prognostic Marker in Minor Salivary Gland Carcinoma.1
303453002018Silencing ELMO3 Inhibits the Growth, Invasion, and Metastasis of Gastric Cancer.0

Citation

Dessen P

ELMO3 (engulfment and cell motility 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-06-01

Online version: http://atlasgeneticsoncology.org/gene/55822/elmo3