| Nomenclature |
|---|
| HGNC (Hugo) | ELOVL4 14415 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ELOVL4 6785 ELOVL fatty acid elongase 4 |
| Aliases | ADMD; CT118; ISQMR; SCA34; |
| STGD2; STGD3 |
| GeneCards (Weizmann) | ELOVL4 |
| Ensembl hg19 (Hinxton) | ENSG00000118402 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000118402 [Gene_View] ENSG00000118402 [Sequence] chr6:79914812-79947598 [Contig_View] ELOVL4 [Vega] |
| ICGC DataPortal | ENSG00000118402 |
| TCGA cBioPortal | ELOVL4 |
| AceView (NCBI) | ELOVL4 |
| Genatlas (Paris) | ELOVL4 |
| WikiGenes | 6785 |
| SOURCE (Princeton) | ELOVL4 |
| Genetics Home Reference (NIH) | ELOVL4 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ELOVL4 - chr6:79914812-79947598 - 6q14.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ELOVL4 - 6q14.1 [Description] (hg19-Feb_2009) |
| GoldenPath | ELOVL4 - 6q14.1 [CytoView hg19] ELOVL4 - 6q14.1 [CytoView hg38] |
| ImmunoBase | ENSG00000118402 |
| Mapping of homologs : NCBI | ELOVL4 [Mapview hg19] ELOVL4 [Mapview hg38] |
| OMIM | 133190 600110 605512 614457 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF277094 AJ420478 AK055277 AK310625 AK312511 |
| RefSeq transcript (Entrez) | NM_022726 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ELOVL4 |
| Cluster EST : Unigene | Hs.101915 [ NCBI ] |
| CGAP (NCI) | Hs.101915 |
| Alternative Splicing Gallery | ENSG00000118402 |
| Gene Expression | ELOVL4 [ NCBI-GEO ] ELOVL4 [ EBI - ARRAY_EXPRESS ]
ELOVL4 [ SEEK ] ELOVL4 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ELOVL4 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 6785 |
| GTEX Portal (Tissue expression) | ELOVL4 |
| Human Protein Atlas | ENSG00000118402-ELOVL4 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9GZR5 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9GZR5 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9GZR5 |
| Splice isoforms : SwissVar | Q9GZR5 |
| PhosPhoSitePlus | Q9GZR5 |
| Domaine pattern : Prosite (Expaxy) | ELO (PS01188) |
| Domains : Interpro (EBI) | ELO_CS ELO_fam ELOVL4 |
| Domain families : Pfam (Sanger) | ELO (PF01151) |
| Domain families : Pfam (NCBI) | pfam01151 |
| Conserved Domain (NCBI) | ELOVL4 |
| DMDM Disease mutations | 6785 |
| Blocks (Seattle) | ELOVL4 |
| Superfamily | Q9GZR5 |
| Human Protein Atlas [tissue] | ENSG00000118402-ELOVL4 [tissue] |
| Peptide Atlas | Q9GZR5 |
| HPRD | 05697 |
| IPI | IPI00009295 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9GZR5 |
| IntAct (EBI) | Q9GZR5 |
| FunCoup | ENSG00000118402 |
| BioGRID | ELOVL4 |
| STRING (EMBL) | ELOVL4 |
| ZODIAC | ELOVL4 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9GZR5 |
| Ontology : AmiGO | protein binding endoplasmic reticulum fatty acid biosynthetic process unsaturated fatty acid biosynthetic process G protein-coupled photoreceptor activity detection of visible light fatty acid elongase activity fatty acid elongase activity fatty acid elongation, saturated fatty acid fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid long-chain fatty-acyl-CoA biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process 3-oxo-arachidoyl-CoA synthase activity 3-oxo-cerotoyl-CoA synthase activity 3-oxo-lignoceronyl-CoA synthase activity very-long-chain 3-ketoacyl-CoA synthase activity |
| Ontology : EGO-EBI | protein binding endoplasmic reticulum fatty acid biosynthetic process unsaturated fatty acid biosynthetic process G protein-coupled photoreceptor activity detection of visible light fatty acid elongase activity fatty acid elongase activity fatty acid elongation, saturated fatty acid fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid long-chain fatty-acyl-CoA biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process 3-oxo-arachidoyl-CoA synthase activity 3-oxo-cerotoyl-CoA synthase activity 3-oxo-lignoceronyl-CoA synthase activity very-long-chain 3-ketoacyl-CoA synthase activity |
| NDEx Network | ELOVL4 |
| Atlas of Cancer Signalling Network | ELOVL4 |
| Wikipedia pathways | ELOVL4 |
| Orthology - Evolution |
|---|
| OrthoDB | 6785 |
| GeneTree (enSembl) | ENSG00000118402 |
| Phylogenetic Trees/Animal Genes : TreeFam | ELOVL4 |
| HOGENOM | Q9GZR5 |
| Homologs : HomoloGene | ELOVL4 |
| Homology/Alignments : Family Browser (UCSC) | ELOVL4 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ELOVL4 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ELOVL4 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ELOVL4 |
| dbVar | ELOVL4 |
| ClinVar | ELOVL4 |
| 1000_Genomes | ELOVL4 |
| Exome Variant Server | ELOVL4 |
| ExAC (Exome Aggregation Consortium) | ENSG00000118402 |
| GNOMAD Browser | ENSG00000118402 |
| Varsome Browser | ELOVL4 |
| Genetic variants : HAPMAP | 6785 |
| Genomic Variants (DGV) | ELOVL4 [DGVbeta] |
| DECIPHER | ELOVL4 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ELOVL4 |
| Mutations |
|---|
| ICGC Data Portal | ELOVL4 |
| TCGA Data Portal | ELOVL4 |
| Broad Tumor Portal | ELOVL4 |
| OASIS Portal | ELOVL4 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ELOVL4 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ELOVL4 |
| Mutations and Diseases : HGMD | ELOVL4 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | Eye diseases - LOVD |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search ELOVL4 |
| DgiDB (Drug Gene Interaction Database) | ELOVL4 |
| DoCM (Curated mutations) | ELOVL4 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ELOVL4 (select a term) |
| intoGen | ELOVL4 |
| Cancer3D | ELOVL4(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 133190 600110 605512 614457 |
| Orphanet | 158 1902 22057 |
| DisGeNET | ELOVL4 |
| Medgen | ELOVL4 |
| Genetic Testing Registry | ELOVL4
|
| NextProt | Q9GZR5 [Medical] |
| TSGene | 6785 |
| GENETests | ELOVL4 |
| Target Validation | ELOVL4 |
| Huge Navigator |
ELOVL4 [HugePedia] |
| snp3D : Map Gene to Disease | 6785 |
| BioCentury BCIQ | ELOVL4 |
| ClinGen | ELOVL4 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 6785 |
| Chemical/Pharm GKB Gene | PA27763 |
| Clinical trial | ELOVL4 |
| Miscellaneous |
|---|
| canSAR (ICR) | ELOVL4 (select the gene name) |
| DataMed Index | ELOVL4 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 54 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ELOVL4 |
| EVEX | ELOVL4 |
| GoPubMed | ELOVL4 |
| iHOP | ELOVL4 |
